Facing the World Physiological Community

Tai Yao
Professor, Fudan University Shanghai Medical College
President, Chinese Association for Physiological Sciences


As a Chinese physiologist, I had the pleasure of attending the 35th Congress of the International Union of Physiological Sciences (IUPS) and had a wonderful time in San Diego. Personally, this was the second time I participated in the IUPS Congress. The first time was in 1989 at Helsinki when I chaired a symposium on acupuncture research. While at the San Diego Congress, I saw the magnificent and substantial progress and changes physiological sciences had made since 1989; I realized more profoundly the future direction of the development of physiological sciences. The reason that I think the San Diego Congress has been a great success is not just the memorable settings and state-of-the-art facilities provided; what is most important is that the organizers have set a right theme and also the scientific program.

“From genomes to functions.” The theme of the Congress has been very precise, explicit, and utterly important. What is more, the Scientific Program Committee chaired by Walter Boron and also the National Organizing Commit-tee chaired by Shu Chien have designed and arranged an excellent program that matches perfectly the theme. I want to mention that the Fenn Lecture given by the Nobel Laureate Peter Agre and the President Lecture delivered by Allen Cowley, and of course many others, are excellent examples demonstrating how to work from genomes to functions, how to translate the achievements of molecular and cell biology to the functions of the complex organisms in health and disease, even though we are just making the first step on our march.

For years, we Chinese physiological scientists have been discussing the development of physiological sciences in the postgenomic era and the importance of promoting translational research and integrative physiology in China. However, in recent years, because of the tremendous advances in molecular and cell biology and the grant funding policies set by the scientific leadership, biomedical research is pushed in the direction of molecular and cellular biology, leaving only a small number of physiological scientists working at the whole body level. Now it becomes evident that pure reductionism has limitations to help us understand the functions of the living body. So what stimulated me the most in San Diego is the advocacy of conducting physiological research in ways that will provide an understanding of the functions of the whole living organism. Of course, this is not a simple way of going back to traditional organ-based physiology; the latest scientific knowledge and advanced state-of-the-art technologies, such as bioinformatics, genomics, proteomics, matabolomics, gene transfer, functional imaging, tissue engineering, nanotechnology, etc., must be emphasized and an interdisciplinary approach must be adopted. As Cowley stated, now is “the time to begin building the scientific infrastructures that will enable an integrated understanding of the function of complex organisms and chronic diseases” (IUPS Newsletter 7, September 2004). In this context, we Chinese physiologists also see opportunities and challenges for the development of life sciences in front of us. We have to learn, to work, to create, and to make significant progress. To achieve this goal, we must make efforts to strengthen the relationship and scientific exchanges and collaborations with our international colleagues.

“Facing the world” is one of the strategies the Chinese Association for Physiological Sciences (CAPS) has formulated. In recent years, China has been making rapid progress in economical and social development. We also made progress in science and technology. But still, there is a big gap between the level in China and the advanced level of the world, and we recognize that the overall impact of Chinese research in physiological sciences is below that of the developed countries. Because of the rapid progress of globalization, we understand that we have to make great efforts to vitalize scientific research and education; also, we must enhance the relations with our international colleagues and catch up with the world advanced level in various fields of science. It was with such wishes, the CAPS sent a delegation participating in the San Diego IUPS Congress. On behalf of the CAPS, I presented a proposal to the IUPS General Assembly, expressing our sincere desire of hosting the 37th IUPS Congress in Beijing, China. Though we did not get it, we experienced pleasure and happiness because our international colleagues gave us very warm encouragement. At the General Assembly, many delegates of various countries came to tell us that our presentation aroused great interest from them, and they encouraged us to make further efforts and wished us success in the future. We Chinese delegates were deeply moved by the friendship our international colleagues showed to us.
The CAPS will celebrate her 80th anniversary in 2006. Nearly 80 years ago, 17 Chinese physiologists formed the Chinese Physiological Society under the leadership of Professor Robert K.S. Lim. Since its establishment, the Society (which changed its name into CAPS in 1953) has been very active in promoting scientific activities and made outstanding contributions in the development of physiological sciences and training of physiological scientists in China. In 1980, the CAPS became an adhering body of the IUPS. This was a very important event for the Chinese physiologists, since participation in an international union would provide us a good platform to communicate with physiologists around the world and forge better relationships with physiologists at distant lands. All these would certainly have impact on us Chinese physiologists. China now adopts a policy of “opening to the world.” During the past two decades, an increasing number of Chinese scientists, including physiologists, went abroad, working in different laboratories and institutions across the world. They play an active role in physiological research and many of them have made contributions to the development of physiological sciences in various fields. Evidently, they also play an important role in promoting the development of science and technology in China. In 2004, the CAPS organized the First International Conference of Chinese Physiological Scientists in Beijing. We had the honor to have Shu Chien, Honorary Member of CAPS, as the Co-Chair and have Allen Cowley, Akimichi Kaneko, and Irene Schulz attending and giving plenary lectures. Having over 200 participants, the conference proved to be a success in uniting the strengths of Chinese physiological scientists around the world and enhancing the research of physiological sciences in China to catch up with the international advances in scientific progress. A decision was made on the meeting that such Conference would be held regularly every four years. The success of this conference further stimulated and strengthened our confidence to host an IUPS Congress in China in the near future. When I was in San Diego, I felt a great happiness because the number of participants from mainland China was much more than the number in previous congresses; also, I saw many participants from various parts of the world were of Chinese origin. At this point, I am very optimistic that, by way of playing an active role on the platform provided by the IUPS, the Chinese physiological scientists will further strengthen the relationship and collaboration with their international colleagues and make their share of contributions to the development of physiological sciences in the world.

A photograph taken at the entrance to the San Diego Convention Center on April 3, 2005, for some of the Chinese physiological scientists attending the 35th IUPS Congress. Third from left in the front row is Tai Yao, author of this article and President of Chinese Association for Physiological Sciences (CAPS). Fourth from left is Shu Chien, Chair of National Organizing Committee of the Congress and Honorary Member of CAPS.

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