On April 15, 2003, the first article of the American Physiological Society’s series, “Physiology in Medicine,” (PIM) to be published in the Annals of Internal Medicine will appear under the leadership of its new Editor, Dennis Ausiello, of Harvard Medical School. The title of this article is “Malignant glioma physiology: cellular response to hypoxia and its role in tumor progression.” Ausiello will be assisted with the series by Dale J. Benos, Deputy Editor (University of Alabama, Birmingham—UAB), and two Associate Editors, Frank Abboud (University of Iowa) and William Koopman (UAB).
The series is in keeping with the strategic plans of the Society, particularly with regards to translational research. Many basic science trainees are focusing their careers on disease-oriented research even though they themselves have not completed medical training. Thus, clinical review articles that relate basic physiological principles to disease are invaluable for this group of scientists. In addition, the editors of Annals, in particular Harold M. Sox, Editor-in-Chief, and Paul Epstein, Deputy Editor, perceived the need and necessity for articles that translated fundamental observations in modern molecular physiology into terms understandable and useful for today’s practicing clinician. Epstein will serve as the PIM Series Editor at Annals.
The PIM series was first published under the banner “Physiology for Physicians” in the New England Journal of Medicine beginning in 1963. Many important articles linking physiological principles to modern medicine appeared in that series. “Physiology in Medicine” then moved to Hospital Practice under the editorship of Thomas E. Andreoli. During his 15-year stewardship, the series moved from Hospital Practice to the American Journal of Medicine.
With the announcement of Andreoli’s retirement from the series, a PIM Task Force was convened in the summer of 2001 to consider the “Physiology in Medicine” series. Members of this task force included Francois Abboud (University of Iowa), Robert J. Alpern (UT Southwestern), Thomas Andreoli (University of Arkansas), Peter Aronson (Yale University), Dale J. Benos (APS Publications Committee Chair), Gerald DiBona (Past President, APS, University of Iowa), Jeffrey M. Drazen (Editor, NEJM, Harvard Medical School), Frank Epstein (Harvard Medical School), Paul Epstein (Deputy Editor, Annals of Internal Medicine), Martin Frank (Executive Director, APS), John Hall (President, APS), Timothy Mapstone (Emory University), Margaret Reich (Director of Publications, APS), Daniel C. Tosteson (Harvard University), and Michael J. Welsh (University of Iowa). This Task Force defined the series, recommended the new Editor to the Publications Committee and APS Council, and chose the new venue for the series.
Thus, the aim of this series is to provide to inquisitive practicing MD’s and/or researchers, an up-to-date physiological understanding of disease with the proper application of new molecular models and tools. The task force members and the Editors feel that the terms “clinically practical” and “scientifically rigorous” are not mutually exclusive. The aim of articles published in this series is to provide a thoughtful and lucid linkage of science to the patient.
The articles will be relatively short and will be simultaneously peer reviewed by the PIM Editors, Associate Editors, and outside referees, as well as by the Editorial Board of Annals of Internal Medicine. Several articles have already been accepted and several more have been submitted and are in the review process. These include articles on pathogenesis of hypertension, thyroid hormone and metabolism, Cushing’s syndrome, scleroderma, asthma, pain, and Alzheimer’s disease. The Editors are open to suggestions from Society members regarding topics that may be of interest. Annals is making the series available online free of charge and there will be a link provided to it on the APS Web site.
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This article is sixth in the series highlighting the features and tools available at the new “portal” site from Stanford’s HighWire Library of the Sciences and Medicine (HWLSM), which allows you to search all of Medline as well as full-text articles from 330 journals, including all the APS journals. The site is at http://highwire.stanford.edu. With the added - and growing - legacy content from the APS journals, this feature is particularly useful for any physiologist. In this issue, we present some effective ways to conduct a search that will quickly find the information you need. The new HWLSM portal provides for very easy search right on the home page at http://highwire.stanford.edu. From this page you can search by author, search for words anywhere in an article, or quickly look up an article by its citation. Most searches can be done right from the home page. Sometimes, however, you may want more precision in your searches, usually to avoid having to look through too many results. You can ‘fine tune’ your searches on the Advanced Search page, shown here (Figure 1). You can reach this page by clicking on the Search button on any page in the portal or by clicking on the Advanced link next to Quick Search. |
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On the Advanced Search page you can do the following:
In addition, from the Advanced Search page you can control the formatting of your search result:
All these options are easy to activate and control from the Advanced Search
page.
In the future the portal will allow you to search by topic, in order to pick
out (for example) articles in circulation without getting articles in vascular
biology, even when a keyword might be used in both fields.
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