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Special Call for Papers
Physiological Genomics

Functional Analysis of Sequence Variation

Technology Development for Physiological Genomics

Computational Modeling of Physiological Systems


Topic: Functional Analysis of Sequence Variation

Physiological Genomics is soliciting manuscript submissions that focus on the analysis of the functional implications of genomic sequence variation. Papers that are responsive to this call can be in any category but will focus on methods and/or research studies that aim to attach physiological relevance to alterations in genes or proteins. Studies should attempt to attach significance to genome deletions, duplications, and single nucleotide polymorphisms and may be undertaken in humans or model organisms, in vitro or in vivo. Theoretical approaches to analysis of sequence variation will also be considered responsive.

Topic: Technology Development for Physiological Genomics

Physiological Genomics is soliciting manuscript submissions that describe the development and/or use of novel technologies in physiological genomics research. It is well recognized that the application of innovative technology has been of major importance to advancements in this field. The early years of this journal coincided with the development of genome-wide techniques and the initial entry of physiologists into the discipline of genomics. The journal has historically published articles that deal with microarray analysis and has led the way in helping to define standards for experiments and publication of microarray results. Physiological Genomics is now interested in embracing the opportunities created by the emergence of new disciplines such as proteomics, metabolomics, next-generation sequencing, modeling, and systems approaches and desires to provide an outlet for studies that explore novel methodologies in these and other fields that will become part of the accepted toolbox of future physiologists.

The “Innovative Methodology” article type is especially well suited to this sort of publication although submissions in all categories will be considered.

Topic: Computational Modeling of Physiological Systems

Physiological Genomics is soliciting original research papers in the area of computational modeling of physiological systems. It is acknowledged that in the coming years, computational modeling and analysis will play a critical role in deciphering large-scale data and developing a systems understanding of biological systems. In particular, the journal is interested in studies that use computational analyses in the context of gene function in physiological systems.