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American Physiological Society
Timeline of
Physiology
1785 - 1853
In 1833, William Beaumont published his remarkable results in a book entitled Experiments and Observations on the Gastric Juice, and the Physiology of Digestion. Beaumont had the fortune of treating and investigating a Canadian voyager, Alexis St. Martin, who had sustained a gunshot wound resulting in a gastric fistula. Under those circumstances, he carried out over seventy experiments, partly in vivo, in the interior of St. Martin's stomach, and the rest with the patient's isolated gastric juice. In this fashion, he came to a series of important conclusions about gastric motility and digestion, especially the effect on meat.
History of Physiology, Karl E. Rothschuh, MD, University of Münster, West-Germany, Robert E. Krieger Publishing Company, 1973
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