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FOR IMMEDIATE RELEASE
- August 25, 2004
- Contact: Stacy Brooks
- American Physiological Society
301.634.7253
sbrooks@the-aps.org
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APS Showcases 46 Historic Breakthrough Research
Articles
Society celebrates 100+ years of
historical physiological research
Bethesda, Md. – August 25, 2004 – The American
Physiological Society (APS) recently embarked on a mission to share more
than 100 years of physiological research through its Legacy Project. The
arduous project that included scanning hundreds of original journal volumes
– the equivalent of more than 200 linear feet of shelf space – dating back
to 1898 has “truly been a labor of love.” To celebrate the completion of
the Legacy Project, APS identified 46 articles published in the APS journals
that have proven vital to the discipline of physiology and the evolution of
modern-day medicine.
“The articles epitomize the ever-evolving thirst for
knowledge and the pioneering spirit of invention that are the signature of
physiology’s best and brightest,” says APS Publications Committee Chair Dale
Benos. “Science owes many advances in technology, equipment and insight
into perplexing physiological processes to this research,” he added.
Featured articles include:
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The
1945 paper authored by Seymour Kety and Carl Schmidt that
introduced a revolutionary new way to measure cerebral blood flow. The
manuscript, still a landmark in its field, sparked the development of new
cerebral blood flow methodologies and revolutionized research on the human
brain.
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Arthur Guyton, Arthur Lindsey and Berwind Kaufmann's 1955 article,
through its pioneering use of systems analysis, placed an emphasis on
venous return as a determinant of cardiac output and became an important
tool for research and teaching.
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The
development of the first three-function blood-gas analyzer, an essential
tool in surgery, anesthesia, intensive care, and emergency medicine, was
detailed in the 1958 article by John Severinghaus and A. Freeman
Bradley. This invention that measures arterial blood for oxygen,
carbon dioxide and pH has proved to be one of the most important
laboratory tests for physicians.
A blue-ribbon panel of physiologists, led by Hershel
Raff of the APS Publications Committee was assembled to select these
landmark articles. Once chosen, APS commissioned eminent scientists with
specialized experience in the field to write essays about a given classic
paper or group of papers. Original authors of the classic papers, where
possible, were invited to provide additional commentary about the work and
times.
The aim of sharing these classic articles and essays is
to stimulate and inspire physiologists of all ages to appreciate the beauty
and the greatness of science published in APS research journals in the last
century. Additionally, APS recognizes the need to make all of its archived
literature accessible, to both serve as a testament to the dedicated
scientists involved in physiological research and to provide a deeper
understanding of the cultural heritage of modern day science.
The Classic articles, introductory essays, and complete
first editions of each journal are freely available on the APS Journals web
site (http://www.the-aps.org/publications/classics/).
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