Translational Human Physiology and Pathophysiology

Understanding the mechanisms that mediate function and dysfunction in the human gastrointestinal tract, liver, and biliary system in health and disease has been enhanced by studies of the human condition itself. Thus, the “-omics” disciplines (such as genomics, transcriptomics, and microbiome) permit studies of the phenotype, genomics, epigenetics, pharmacogenomics, and microbiome in biological samples obtained from humans (healthy or diseased). Such studies may be aligned with characterization of the phenotype in order to explore physiological or pathophysiological mechanisms of the human condition. This discipline can also be complemented by the more specific insights that can be obtained in human models of disease, such as transgenic or knockout animal models, or germ-free animals with specific microbial perturbations. Studies based on translational biology are instrumental to elucidate the mechanisms of the human gastrointestinal tract and liver in health and disease and will be of great interest to readers of the American Journal of Physiology-Gastrointestinal and Liver Physiology.

All manuscripts should be submitted online via eJournalPress.. During the online submission process, under the “Classifications" folder, please use the “Category” drop-down menu and select “Call for Papers: Translational Human Physiology and Pathophysiology.”

Manuscripts will undergo normal peer review as they are received. Accepted manuscripts will be published online as they are accepted. Articles published from this Call for Papers will be highlighted at the time of publication. The collection may also include specially commissioned review or research articles related to the topic.

Manuscripts can be submitted anytime, but to be eligible for inclusion in this Call for Papers, manuscripts must be submitted by April 30, 2019.