The Gut Microbiome: A Virtual Organ.

The gut microbiome plays an essential role in the maintenance of health of the gastrointestinal tract that until recently has been underestimated. Components of the microbiome from individual taxa to ecosystem ecology are also recognized to feature in a large number of diseases, ranging from obesity to inflammatory bowel diseases to colorectal cancer. Previous, correlative work has highlighted the potential involvement of the gut microbiome in both health and disease. Studies that elucidate the mechanisms and consequences of such interactions are now needed to define the human-microbiome relationship. The physiological mechanisms that underlie bidirectional interactions between the host and the microbiome relationship are of growing interest to readers of the American Journal of Physiology-Gastrointestinal and Liver Physiology. The Journal welcomes research articles that address the mechanisms of host-microbiome interactions, as well as review articles that summarize the current state of knowledge and identify gaps that might be filled by future work.

All manuscripts should be submitted online via eJournalPress. During the online submission process, under the “Classifications" folder, please use the “Category” drop-down menu and select “Call for Papers: The Gut Microbiome: A Virtual Organ.”

Manuscripts will undergo normal peer review as they are received. Accepted manuscripts will be published online as they are accepted. Articles published from this Call for Papers will be highlighted at the time of publication. The collection may also include specially commissioned review or research articles related to the topic.

Manuscripts can be submitted anytime, but to be eligible for inclusion in this Call for Papers, manuscripts must be submitted by April 30, 2019.

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