Regulation of Coronary Blood Flow in Normal and Ischemic States

Consulting Editors Johnathan Tune and Donal O’Leary, and Guest Editor Judy Muller-Delp, along with the editorial team of AJP-Heart and Circulatory Physiology, invite submission of manuscripts on the regulation of coronary blood flow in normal and ischemic states.

Extensive research over the past 50+ years has focused on elucidation of the mechanisms responsible for the control of coronary microvascular resistance in response to a variety of physiologic and pathophysiologic stimuli. While studies have identified that metabolic, myogenic, endothelial, and neural-mediated pathways each influence myocardial perfusion, understanding of the integrative mechanisms responsible for the regulation of coronary blood flow and its impact on ventricular function remains rather limited. Accordingly, the editors welcome manuscript submissions (original research, perspectives, and review articles) to address the regulation of the coronary circulation in health and disease. In particular, the editors are interested in submissions investigating novel paradigms of coronary control and encourage discussion of translational perspectives and identification of essential unanswered questions that require future research.

We will consider both original research articles and review articles. For review articles only, authors should email the editorial office ( a pre-submission inquiry including a working title, author and affiliation lists, abstract, and brief outline of the content for approval by the editors.

All manuscripts should be submitted online at During the online submission process, under the "Keywords & Special Sections" tab, please use the "Category" drop-down menu and select “Call for Papers: Regulation of Coronary Blood Flow in Normal and Ischemic States."

Manuscripts will undergo normal peer review as they are received. Accepted manuscripts will be published online as they are accepted. Articles published from this Call for Papers will be highlighted at the time of publication. All manuscripts accepted from this Call for Papers will be included in an online article collection to further highlight the importance of this topic. The article collection will also include specially commissioned Review articles on the topic.

Manuscripts can be submitted anytime, but to be eligible for inclusion in this Call for Papers, manuscripts must be submitted by June 30, 2019. If you have any questions please contact Kara Hansell Keehan, Executive Editor, via email at