The Gut-Liver Axis

The gut is the largest mucosal surface of the body. It interacts with numerous environmental factors derived from the diet and the intestinal microbiota. The immune system of the gut is confronted with the complex task of differentiating beneficial from harmful nutrients and microbes. The gut is also a major source of hormones and inflammatory mediators. The liver is directly connected to the gut and is the first organ to receive signals from the gut-derived metabolites, cytokines/chemokines, immune cells, and hormones. Considering the central role that the liver plays in metabolism and immune regulation, studies that examine the mechanisms of the gut/liver axis will be of interest to the readership of the American Journal of Physiology-Gastrointestinal and Liver Physiology.

All manuscripts should be submitted online via eJournalPress. During the online submission process, under the “Keywords & Special Sections” tab, please use the “Category” drop-down menu and select “Call for Papers: The Gut-Liver Axis”.

Manuscripts will undergo normal peer review as they are received. Accepted manuscripts will be published online as they are accepted. Articles published from this Call for Papers will be highlighted at the time of publication. The collection may also include specially commissioned research articles related to the topic.

Manuscripts can be submitted anytime, but to be eligible for inclusion in this Call for Papers, manuscripts must be submitted by October 1, 2018.