Brain-Gut Interactions

In recent years, the bidirectional brain-gut axis has emerged as a key mediator, regulator, and determinant of gastrointestinal, pancreatic, and hepatic functions, feeding behavior, pain, and metabolic regulation in both physiological and pathophysiological states. Dysregulation of both afferent and efferent signaling between the gut and the central nervous system has been linked to the pathogenesis and exacerbation of diseases that span from enteric neuropathies to developmental and metabolic disorders, as well as to neurological diseases (e.g., Parkinson’s disease). The interface of the gut-brain axis with the microbiome (i.e., microbiota-gut-brain axis) and with the immune system may contribute greatly to the understanding of idiopathic pathologies. Articles focused on understanding the mechanistic involvement of gut-brain signaling to homeostasis and disease are of great interest to the readers of the American Journal of Physiology-Gastrointestinal and Liver Physiology.

All manuscripts should be submitted online via eJournalPress.. During the online submission process, under the “Classifications" folder, please use the “Category” drop-down menu and select “Call for Papers: Brain-Gut Interactions."

Manuscripts will undergo normal peer review as they are received. Accepted manuscripts will be published online as they are accepted. Articles published from this Call for Papers will be highlighted at the time of publication. The collection may also include specially commissioned review or research articles related to the topic.

Manuscripts can be submitted anytime, but to be eligible for inclusion in this Call for Papers, manuscripts must be submitted by April 30, 2019.