The American Physiological Society Press Release

press release logo

APS Contact: APS Communications Office

Email: communications@the-aps.org

Phone: 301.634.7209

Twitter: @APSPhysiology


Electrical Stimulation Improves Paralyzed Patients’ Function

Therapy helps produce movement and sensation after spinal cord injury

Bethesda, Md. (September 14, 2017)—Nearly 282,000 people in the U.S. live with paralysis following a spinal cord injury (SCI). A review of more than 90 studies found that electrical stimulation may help restore function in those paralyzed after SCI. The article is published in Physiology.

SCI can cause paralysis in the arms, legs or both, limiting physiological functions such as movement, bladder and bowel control, and temperature regulation. Electrical stimulation, a treatment first developed in the 1960s to treat pain, has been studied as a means to restore movement in paralyzed limbs. Three types of stimulation therapies discussed in the review and found to be effective include:

  • Epidural spinal stimulation—electrodes placed outside the covering of the spinal cord with a device implanted under the skin to generate electrical pulses—relieved muscle tightness and improved leg extension, sensation, hand function and bladder control even after therapy ended;
  • Transcutaneous stimulation—electrodes applied to the skin’s surface and using an external pulse generator—improved muscle tightness and stepping ability; and
  • Intraspinal stimulation—electrodes implanted directly in the spinal cord; studied mostly in animals—enhanced reaching, grasping and stepping movements by directly activating nerve cells responsible for movement (motoneurons).

Electrical stimulation may be most effective for SCI-related paralysis when combined with physical therapy and medications that encourage the spinal cord to form new neural pathways. “Going forward, careful and systematic evaluation of therapeutic stimulation approaches and their combinations with molecular and cellular interventions may be necessary to deliver effective new treatments to benefit people with spinal cord injuries,” the authors wrote.

Read the full article, “Therapeutic stimulation for restoration of function after spinal cord injury,” in the September issue of Physiology.

NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact the APS Communications Office or 301-634-7209. Find more research highlights in the APS Press Room.

Physiology is the study of how molecules, cells, tissues and organs function in health and disease. Established in 1887, the American Physiological Society (APS) was the first U.S. society in the biomedical sciences field. The Society represents more than 10,500 members and publishes 15 peer-reviewed journals with a worldwide readership.

 


From: 
Email:  
To: 
Email:  
Subject: 
Message:

~/Custom.Templates/PressRelease.aspx