Animal Research
Mice are the most commonly used mammals in medical research. Image © Understanding Animal ResearchMedical research involving animals is beneficial to both humans and other animals. Certain kinds of questions can only be answered through animal studies. This section provides background and analysis of both animal research in general and specific animal research issues.

Current Issues

APS Urges OLAW to Revise “Significant Changes” Guidance

On March 11, 2014, OLAW published a request for comments on proposed guidance about what constitute “significant” changes to ongoing animal research activities. APS urged that a proposed revision to the guidance be revised to avoid “increas[ing] administrative burden rather than reduc[ing] it.”

APS Asks Wildlife Service to Continue Chimpanzee Research

Biomedical research with captive chimpanzees should be allowed to continue, the American Physiological Society said in comments to the U.S. Fish and Wildlife Service. This was the central tenet of the APS response to a proposal that would classify captive chimpanzees as endangered under the Endangered Species Act.

Italian Scientists Urge Research Restrictions Be Rejected

A group of Italian scientists is seeking to draw attention to recently-approved legislation that could severely restrict animal research in that country.

Publications

Animal Research: Finding Cures, Saving Lives

Check out animalresearchcures.org for our updated FAQ on animal research, the free PDF, and other helpful resources.

Resource Book for the Design of Animal Exercise Protocols

APS’s Resource Book for the Design of Animal Exercise Protocols offers suggestions for how to design, review, and implement experimental paradigms involving animals and exercise.

Animal Labs

DOD Report: Animals Still Needed for Trauma Training

Alternative training methods cannot yet replace the use of live animals in the training of combat medics, the Department of Defense (DOD) told Congress. The finding was part of a report mandated under the FY 2013 National Defense Authorization Act.

The Evolving Role of Animal Laboratories in Physiology Instruction

Published in Advances in Physiology Education, this article provides historical perspective review on animal teaching laboratories in medical education, including an evaluation of the methodologies and conclusions of several studies sometimes cited by those who oppose of live animal labs.

Animal Research Intro

Regulation of Animal Research in the U.S.

Animal research is subject to a number of layers of regulation and oversight.

Government and Other Oversight Resources

Information on animal research oversight and regulation.

Security

APS Condemns Threats Against Researchers

The American Physiological Society condemns all acts of violence or intimidation against individuals engaged in legitimate scientific inquiries intended to advance knowledge and improve health.

Statements Condemning Animal Rights Extremism

Statements from societies, universities, federal agencies, and others condemning attacks and harassment targeted at researchers.

NIH Preparedness Guide

Advice from NIH on how to mitigate the threat of animal rights extremists.

Public Outreach Toolkit

Symposium Summary: Public Outreach—A Toolkit for Investigators

Highlights from the APS Animal Care and Experimentation Committee EB2012 symposium on Public Outreach.
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