Oliver Smithies
Oliver SmithiesOliver Smithies - Nobel Laureate

Oliver Smithies was awarded the 2007 Nobel Prize in Physiology or Medicine for discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells.

Articles:


  1. Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney
    American Journal of Physiology - Renal Physiology Published 15 December 2012 Vol. 303 no. 12, F1629-F1640 DOI: 10.1152/ajprenal.00246.2012

  2. Amino acids as modulators of endothelium-derived nitric oxide
    American Journal of Physiology - Renal Physiology Published 6 July 2006 Vol. 291 no. 2, F297-F304 DOI: 10.1152/ajprenal.00417.2005

  3. Kidney function in mice lacking aldosterone
    American Journal of Physiology - Renal Physiology Published 9 December 2005 Vol. 290 no. 1, F61-F69 DOI: 10.1152/ajprenal.00257.2005

  4. Lifelong genetic minipumps
    Physiological Genomics Published 20 January 2005 Vol. 20 no. 2, 203-209 DOI: 10.1152/physiolgenomics.00221.2004

  5. A γGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice
    Physiological Genomics Published 11 August 2004 Vol. 18 no. 3, 290-298 DOI: 10.1152/physiolgenomics.00120.2003

  6. Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion
    American Journal of Physiology - Renal Physiology Published 3 September 2003 Vol. 285 no. 4, F694-F702 DOI: 10.1152/ajprenal.00097.2003

  7. Estrogen-induced osteogenesis in intact female mice lacking ERβ
    American Journal of Physiology - Endocrinology and Metabolism Published 1 October 2002 Vol. 283 no. 4, E817-E823 DOI: 10.1152/ajpendo.00071.2002

  8. Ventricular expression of natriuretic peptides inNpr1 −/− mice with cardiac hypertrophy and fibrosis
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 August 2002 Vol. 283 no. 2, H707-H714 DOI: 10.1152/ajpheart.00677.2001

  9. Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 January 2002 Vol. 282 no. 1, H58-H65

  10. Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d
    Physiological Genomics Published 6 June 2001 Vol. 6 no. 1, 45-55

  11. Abnormal water metabolism in mice lacking the type 1A receptor for ANG II
    American Journal of Physiology - Renal Physiology Published 1 January 2000 Vol. 278 no. 1, F75-F82

  12. Tubuloglomerular feedback in ACE-deficient mice
    American Journal of Physiology - Renal Physiology Published 1 May 1999 Vol. 276 no. 5, F751-F757

  13. Genetic disruption of atrial natriuretic peptide causes pulmonary hypertension in normoxic and hypoxic mice
    American Journal of Physiology - Lung Cellular and Molecular Physiology Published 1 May 1999 Vol. 276 no. 5, L868-L874

  14. Renal growth and development in mice lacking AT1A receptors for angiotensin II
    American Journal of Physiology - Renal Physiology Published 1 January 1998 Vol. 274 no. 1, F43-F50

  15. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation
    American Journal of Physiology - Renal Physiology Published 1 April 1997 Vol. 272 no. 4, F515-F520

  16. Blood pressure and fluid-electrolyte balance in mice with reduced or absent ANP
    American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Published 1 July 1996 Vol. 271 no. 1, R109-R114

  17. Some thermodynamic and kinetic aspects of metabolic phosphorylation
    Physiological Reviews Published 1 July 1948 Vol. 28 no. 3, 283-303 


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