Louis J. Ignarro
Louis J. IgnarroLouis J. Ignarro  - Nobel Laureate

Louis J. Ignarro was awarded the 1998 Nobel Prize in Physiology or Medicine for discovery that nitric oxide (NO) acts as a signaling molecule in the cardiovascular system.

Articles:
  1. IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells
    American Journal of Physiology - Cell Physiology Published 6 May 2008 Vol. 294 no. 5, C1198-C1205 DOI: 10.1152/ajpcell.00325.2007

  2. Free radical biology and medicine: it's a gas, man!
    American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Published 1 September 2006 Vol. 291 no. 3, R491-R511 DOI: 10.1152/ajpregu.00614.2005

  3. Gastrointestinal motility during pregnancy: role of nitrergic component of NANC nerves
    American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Published 1 October 2000 Vol. 279 no. 4, R1478-R1485

  4. IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells
    American Journal of Physiology - Cell Physiology Published 1 July 2000 Vol. 279 no. 1, C248-C256

  5. NG-hydroxy-l-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms
    American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Published 1 October 1998 Vol. 275 no. 4, R1256-R1264

  6. Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 November 1996 Vol. 271 no. 5, H1988-H1998

  7. Nitric oxide regulates endothelium-dependent vasodilator responses in rabbit hindquarters vascular bed in vivo
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 July 1996 Vol. 271 no. 1, H133-H139

  8. NO is more important than PGI2 in maintaining low vascular tone in feto-placental vessels
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 December 1993 Vol. 265 no. 6, H2036-H2043

  9. Influence of Zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed
    Journal of Applied Physiology Published 1 April 1993 Vol. 74 no. 4, 1704-1711

  10. Nitric oxide and cGMP: mediators of pelvic nerve-stimulated erection in dogs
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 February 1993 Vol. 264 no. 2, H419-H422

  11. Electrical field stimulation causes endothelium-dependent and nitric oxide-mediated relaxation of pulmonary artery
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 April 1992 Vol. 262 no. 4, H973-H979

  12. Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 February 1992 Vol. 262 no. 2, H616-H620

  13. L-arginine-dependent vascular smooth muscle relaxation and cGMP formation
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 December 1990 Vol. 259 no. 6, H1813-H1821 

  14. Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP
    American Journal of Physiology - Heart and Circulatory Physiology Published 1 November 1987 Vol. 253 no. 5, H1074-H1082

  15. Atriopeptin II relaxes and elevates cGMP in bovine pulmonary artery but not vein
    Journal of Applied Physiology Published 1 April 1986 Vol. 60 no. 4, 1128-1133



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