Listed below are the articles which have been singled out as APS Classic Papers. These articles have been made free for viewing by all users.
Ahlquist RP. A study of adrenotropic receptors. Am J Physiol 153: 586-600, 1948.
Berne RM. Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. Am J Physiol 204: 317-322, 1963.
Cannon WB. The emergency function of the adrenal medulla in pain and the major emotions. Am J Physiol 33: 356-372, 1914.
Cannon WB. Studies on the conditions of activity in endocrine glands. V. The isolated heart as an indicator of adrenal secretion induced by pain, asphyxia and excitement. Am J Physiol 50: 399-432, 1919.
Cannon WB and de la Paz D. Emotional stimulation of adrenal secretion. Am J Physiol 28: 64-70, 1911.
Comroe JH Jr. The location and function of the chemoreceptors of the aorta. Am J Physiol 127: 176-191, 1939.
Critchlow V, Liebelt RA, Bar-Sela M, Mountcastle W, and Lipscomb HS. Sex difference in resting pituitary-adrenal function in the rat. Am J Physiol 205: 807–815, 1963.
Cross RJ and Taggart JV. Renal tubular transport: accumulation of p-aminohippurate by rabbit kidney slices. Am J Physiol 161: 181–190, 1950.
Duarte CG, Chomety F, and Giebisch G. Effect of amiloride, ouabain, and furosemide on distal tubular functiion in the rat. Am J Physiol 221: 632-639, 1971.
Falk, G. Maturation of renal function in infant rats. Am J Physiol 181: 157-170, 1955.
Fitts RH, Booth FW, Winder WW, Holloszy JO. Skeletal muscle respiratory capacity, endurance, and glycogen utilization. Am J Physiol 228: 1029–1033, 1975.
Fenn WO, Rahn H, and Otis AB. A theoretical study of the composition of the alveolar air at altitude. Am J Physiol 146: 637-653, 1946.
Fevold HL, Hisaw FL, Leonard SL. The gonad stimulating and the luteinizing hormones of the anterior lobe of the hypophysis. Am J Physiol 97: 291-301, 1931.
Fowler WS. Lung function studies. II. The respiratory dead space. Am J Physiol 154: 405-416, 1948.
Gottschalk CW, Lassiter WE, Mylle M, Ullrich KJ, Schmidt-Nielsen B, O'Dell R, and Pehling G. Micropuncture study of composition of loop of Henle fluid in desert rodents. Am J Physiol 204: 532-535, 1963.
Gottschalk CW and Mylle M. Micropuncture study of the mammalian urinary concentrating mechanism: evidence for the countercurrent hypothesis. Am J Physiol 196: 927-936, 1959.
Guyton AC, Lindsey AW, and Kaufmann BN. Effect of mean circulatory filling pressure and other peripheral circulatory factors on cardiac output. Am J Physiol 180: 463-468, 1955.
Hammel HT, Hardy JD, and Fusco MM. Thermoregulatory responses to hypothalamic cooling in unanesthetized dogs. Am J Physiol 198: 481-486, 1960.
Hellstrom B and Hammel HT. Some characteristics of temperature regulation in the unanesthetized dog. Am J Physiol 213: 547-556, 1967.
Houssay BA and Lewis JT. The relative importance to life of cortex and medulla of the adrenal glands. Am J Physiol 64: 512-521, 1923.
Ingle DJ. The effects of administering large amounts of cortin on the adrenal cortices of normal and hypophysectomized rats. Am J Physiol 124: 369–371, 1938
Ingraham RC and Visscher MB. Further studies on intestinal absorption with the performance of osmotic work. Am J Physiol 121: 771-785, 1938.
Jolliffe N, Shannon JA, and Smith HW. The excretion of urine in the dog. III. The use of non-metabolized sugars in the measurement of the glomerular filtrate. Am J Physiol 100: 301-312, 1932.
Kety SS, and Schmidt CF. The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations. Am J Physiol 143: 53-66, 1945.
Landis EM. The capillary pressure in frog mesentery as determined by micro-injection methods. Am J Physiol 75: 548-570, 1926.
Landis EM. Micro-injection studies of capillary permeability. II. The relation between capillary pressure and the rate at which fluid passes through the walls of single capillaries. Am J Physiol 82: 217-238, 1927.
Malnic G, Klose RM, and Giebisch G. Micropuncture study of renal potassium excretion in the rat. Am J Physiol 206: 674-686, 1964.
Malnic G, Klose RM, and Giebisch G. Micropuncture study of distal tubular potassium and sodium transport in rat nephron. Am J Physiol 211: 529-547, 1966.
Malnic G, Klose RM, and Giebisch G. Microperfusion study of distal tubular potassium and sodium transfer in rat kidney. Am J Physiol 211: 548-559, 1966.
Malnic G, Mello Aires M, and Giebisch G. Potassium transport across renal distal tubules during acid-base disturbances. Am J Physiol 221: 1192-1208, 1971.
Margaria R, Edwards HT, and Dill DB. The possible mechanisms of contracting and paying the oxygen debt and the role of lactic acid in muscular contraction. Am J Physiol 106: 689–715, 1933.
Marine D and Baumann EJ. Duration of life after suprarenalectomy in cats and attempts to prolong it by injections of solutions containing sodium salts, glucose and glycerol. Am J Physiology 81: 86-100, 1927.
McGregor DD, Smirk FH. Vascular responses to 5-hydroxytryptamine in genetic and renal hypertensive rats. Am J Physiol 219: 687–690, 1970.
Motley, HL, Cournand, A, Werko, L, Himmelstein, A, Dresdale, D. The influence of short periods of induced acute anoxia upon pulmonary artery pressures in man. Am J Physiol 150: 315-320, 1947.
Neely JR, Liebermeister H, Battersby EJ, and Morgan HE. Effect of pressure development on oxygen consumption by isolated rat heart. Am J Physiol 212: 804–814, 1967.
Pappenheimer JR and Soto-Rivera A. Effective osmotic pressure of the plasma proteins and other quantities associated with the capillary circulation in the hind limbs of cats and dogs. Am J Physiol 152: 471-491, 1948
Pappenheimer JR, Renkin EM and Borrero LM. Filtration, diffusion and molecular sieving through peripheral capillary membranes: A contribution to the pore theory of capillary permeability. Am J Physiol 167: 13-46, 1951.
Pitts RF and Alexander, RS. The nature of the renal tubular mechanism for acidifying the urine. Am J Physiol 144: 239-254, 1945.
Pitts RF and Lotspeich WD. Bicarbonate and the renal regulation of acid base balance. Am J Physiol 147:138-154, 1946.
Rahn H. A concept of mean alveolar air and the ventilation-bloodflow relationships during pulmonary gas exchange. Am J Physiol 158: 21-30, 1949.
Richards AN and Walker AM. Methods of collecting fluid from known regions of the renal tubules of Amphibia and of perfusing the lumen of a single tubule. Am J Physiol 118: 111-120, 1936.
Riddle O, Bates RW, and Dykshorn SW. The preparation, identification and assay of prolactin—a hormone of the anterior pituitary. Am J Physiol 105: 191-216, 1933.
Sarnoff SJ, Braunwald E, Welch GH Jr, Case RB, Stainsby WN, and Macruz R. Hemodynamic determinants of oxygen consumption of the heart with special reference to the tension-time index. Am J Physiol 192: 148–156, 1957.
Schmidt-Nielsen B. Renal tubular excretion of urea in kangaroo rats. Am J Physiol 170: 45–56, 1952.
Schmidt-Nielsen B. Urea excretion in white rats and kangaroo rats as influenced by excitement and by diet. Am J Physiol 181: 131–139, 1955.
Schmidt-Nielsen B, Osaki H, Murdaugh HV Jr, and O'Dell R. Renal regulation of urea excretion in sheep. Am J Physiol 194: 221–228, 1958.
Shannon JA. The excretion of inulin by the dog. Am J Physiol 112: 405-413, 1935.
Shannon JA and Fisher S. The renal tubular reabsorption of glucose in the normal dog. Am J Physiol 122: 765-774, 1938.
Shannon JA, Farber S, and Troast L. The measurement of glucose Tm in the normal dog. Am J Physiol 133: 752-761, 1941.
Swingle WW and Pfiffner JJ. Studies on the adrenal cortex. I. The effect of a lipid fraction upon the life-span of adrenalectomized cats. Am J Physiol 96: 153-163, 1931.
Truniger B and Schmidt-Nielsen B. Intrarenal distribution of urea and related compounds: effect of nitrogen intake. Am J Physiol 207: 971–978, 1964.
Ullrich KJ, Schmidt-Nielsen B, O'Dell R, Pehling G, Gottschalk CW, Lassiter WE, and Mylle M. Micropuncture study of composition of proximal and distal tubular fluid in rat kidney. Am J Physiol 204: 527-531, 1963.
Visscher MB, Fetcher ES Jr, Carr CW, Gregor HP, Bushey MS, and Barker DE. Isotopic tracer studies on the movement of water and ions between intestinal lumen and blood. Am J Physiol 142: 550-575, 1944.
Walker AM, Bott PA, Oliver J, and MacDowell MC. The collection and analysis of fluid from single nephrons of the mammalian kidney. Am J Physiol 134: 580-595, 1941.
Walker AM and Hudson CL. The reabsorption of glucose from the renal tubule in Amphibia and the action of phlorhizin upon it. Am J Physiol 118: 130-143, 1936.
Walker AM and Oliver J. Methods for the collection of fluid from single glomeruli and tubules of the mammalian kidney. Am J Physiol 134: 562-579, 19414.
Wall JS, Steele R, de Bodo RC, and Altszuler N. Effect of insulin on utilization and production of circulating glucose. Am J Physiol 189: 43–50, 1957.
Wearn JT and Richards AN. Observations on the composition of glomerular urine, with particular reference to the problem of reabsorption in the renal tubules. Am J Physiol 71: 209-227, 1924.
Wright FS, Strieder N, Fowler N, and Giebisch G. Potassium secretion by distal tubule after potassium adaptation. Am J Physiol 221: 437-448, 1971.
Gollnick PD, Armstrong RB, Saubert CW IV, Piehl K, and Saltin B. Enzyme activity and fiber composition in skeletal muscle of untrained and trained men. J Appl Physiol 33: 312-319, 1972.
Gollnick PD, Armstrong RB, Saltin B, Saubert CW IV, Sembrowich WL, and Shepherd RE. Effect of training on enzyme activity and fiber composition of human skeletal muscle. J Appl Physiol 34: 107-111, 1973.
Hammel HT, Jackson DC, Stolwijk JAJ, Hardy JD, and Strømme SB. Temperature regulation by hypothalamic proportional control with an adjustable set point. J Appl Physiol 18: 1146-1154, 1963.
Howell JBL, Permutt S, Proctor DF, and Riley RL. Effect of inflation of the lung on different parts of pulmonary vascular bed. J Appl Physiol 16: 71-76, 1961.
Murdaugh HV Jr, Schmidt-Nielsen B, Doyle EM, and O'Dell R. Renal tubular regulation of urea excretion in man. J Appl Physiol 13: 263–268, 1958.
Permutt S, Howell JBL, Proctor DF, and Riley RL. Effect of lung inflation on static pressure-volume characteristics of pulmonary vessels. J Appl Physiol 16: 64-70, 1961.
Riley RL and Cournand A. "Ideal" alveolar air and the analysis of ventilation-perfusion relationships in the lungs. J Appl Physiol 1: 825-847, 1949.
Riley RL and Cournand A. Analysis of factors affecting partial pressures of oxygen and carbon dioxide in gas and blood of lungs: theory. J Appl Physiol 4: 77-101, 1951.
Severinghaus, JW, and Bradley, AF. Electrodes for blood Po2 and Pco2 determination. J Appl Physiol 13: 515-520, 1958.
Bessou P and Perl ER. Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli. J Neurophysiol 32: 1025–1043, 1969.
Christensen BN and Perl ER. Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn. J Neurophysiol 33: 293–307, 1970.
Dowling JE and Werblin FS. Organization of retina of the mudpuppy, Necturus maculosus. I. Synaptic structure. J Neurophysiol 32: 315–338, 1969.
Fernandez C and Goldberg JM. Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. I. Response to static tilts and to long-duration centrifugal force. J Neurophysiol 39: 970–984, 1976.
Fernandez C and Goldberg JM. Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. II. Directional selectivity and force-response relations. J Neurophysiol 39: 985–995, 1976.
Fernandez C and Goldberg JM. Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. III. Response dynamics. J Neurophysiol 39: 996–1008, 1976.
Funahashi S, Bruce CJ, and Goldman-Rakic PS. Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. J Neurophysiol 61: 331–349, 1989.
Goldberg JM and Brown PB. Response of binaural neurons of dog superior olivary complex to dichotic tonal stimuli: some physiological mechanisms of sound localization. J Neurophysiol 32: 613–636, 1969.
Grafstein B. Mechanism of spreading cortical depression. J Neurophysiol 19: 154–171, 1956.
Henneman E, Somjen G, and Carpenter DO. Functional significance of cell size in spinal motoneurons. J Neurophysiol 28: 560–580, 1965.
Henneman E and Olson CB. Relations between structure and function in the design of skeletal muscles. J Neurophysiol 28: 581–598, 1965.
Henneman E, Somjen G, and Carpenter DO. Excitability and inhibitability of motoneurons of different sizes. J Neurophysiol 28: 599–620, 1965.
Kravitz EA, Kuffler SW, and Potter DD. Gamma-aminobutyric acid and other blocking compounds in Crustacea. III. Their relative concentrations in separated motor and inhibitory axons. J Neurophysiol 26: 739–751, 1963.
Kuffler SW. Discharge patterns and functional organization of mammalian retina. J Neurophysiol 16: 37–68, 1953.
Leão AAP. Spreading depression of activity in the cerebral cortex. J Neurophysiol 7: 359–390, 1944.
Leão AAP. Pial circulation and spreading depression of activity in the cerebral cortex. J Neurophysiol 7: 391–396, 1944.
Leão AAP. Further observations on the spreading depression of activity in the cerebral cortex. J Neurophysiol 10: 409–414, 1947.
Marmarelis PZ and Naka K-I. Nonlinear analysis and synthesis of receptive-field responses in the catfish retina. II. One-input white-noise analysis. J Neurophysiol 36: 619–633, 1973.
McPhedran AM, Wuerker RB, and Henneman E. Properties of motor units in a homogeneous red muscle (soleus) of the cat. J Neurophysiol 28: 71–84, 1965.
Naka K-I and Nye PW. Role of horizontal cells in organization of the catfish retinal receptive field. J Neurophysiol 34:785–801, 1971.
Naka K-I, Marmarelis PZ, and Chan RY. Morphological and functional identifications of catfish retinal neurons. III. Functional identification. J Neurophysiol 38: 92–131, 1975.
Otsuka M, Kravitz EA, and Potter DD. Physiological and chemical architecture of a lobster ganglion with particular reference to gamma-aminobutyrate and glutamate. J Neurophysiol 30: 725–752, 1967.
Rall W. Distinguishing theoretical synaptic potentials computed for different soma-dendritic distributions of synaptic input. J Neurophysiol 30: 1138–1168, 1967.
Rall W, Burke RE, Smith TG, Nelson PG, and Frank K. Dendritic location of synapses and possible mechanisms for the monosynaptic EPSP in motoneurons. J Neurophysiol 30: 1169–1193, 1967.
Rall W and Shepherd GM. Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb. J Neurophysiol 31: 884–915, 1968.
Segev I and Rall W. Computational study of an excitable dendritic spine. J Neurophysiol 60: 499–523, 1988.
Sperry RW. Optic nerve regeneration with return of vision in anurans. J Neurophysiol 7: 57–69, 1944.
Sperry RW. Restoration of vision after crossing of optic nerves and after contralateral transplantation of eye. J Neurophysiol 8: 15–28, 1945.
Werblin FS and Dowling JE. Organization of the retina of the mudpuppy, Necturus maculosus. II. Intracellular recording. J Neurophysiol 32: 339–355, 1969.
Wuerker RB, McPhedran AM, and Henneman E. Properties of motor units in a heterogeneous pale muscle (m. gastrocnemius) of the cat. J Neurophysiol 28: 85–99, 1965.
Wurtz RH. Visual receptive fields of striate cortex neurons in awake monkeys. J Neurophysiol 32: 727–742, 1969.
Wurtz RH. Comparison of effects of eye movements and stimulus movements on striate cortex neurons of the monkey. J Neurophysiol 32: 987–994, 1969.
Yin TCT and Chan J. Interaural time sensitivity in medial superior olive of cat. J Neurophysiol 64: 465–488, 1990.