Sadis Matalon, Ph.D., Sc.Dr. (Hon.)
Dr. Sadis Matalon was born in Athens, Greece on October 6th, 1948 and came to the United States in 1966 as an undergraduate Fullbright Scholar. He received a BA from Macalester College, cum laude with Special Departmental Honors in Physics in 1970. He then enrolled at the University of Minnesota where he earned a Master of Science in Physics in 1973 and a PhD in Physiology in 1975 on lung fluid balance in the newborn lung under the mentorship of O. D. Wangensteen. At the University of Minnesota he also worked with Dr. Arnold Leonard and Dr. Carl Hunt on quantifying abnormalities of gas exchange in premature infants with hyaline membrane disease using mass spectrometry. After spending a year as an Associate in the Departments of Pediatrics (Childrens Hospital) and Physiology in Northwestern University, Chicago, IL, he moved to the Department of Physiology at the University of Buffalo, as a Research Assistant Professor (1966), where he worked with Dr. Farhi on gas exchange and ventilation perfusion abnormalities and on pulmonary oxygen toxicity. He was promoted to Assistant Professor in 1977 and to Associate Professor with tenure at 1982. During this time, he worked closely with Drs. Notter and Holm from the University of Rochester to study physiological, biochemical and biophysical injury to pulmonary surfactant in acute lung injury in vivo and in vitro.
At 1987 he moved to the Department of Anesthesiology of the University of Alabama at Birmingham to do a sabbatical on free radical biochemistry in Dr. Freeman’s laboratory; he remained at UAB ever since. While at UAB he collaborated with Dr. Benos (deceased) to elucidate the biochemical and biophysical nature of ion channels in lung epithelial cells. He also concentrated on identifying basic mechanisms by which reactive species altered lung ion channel and pulmonary surfactant structure function relationships in vivo and in vitro. He was named the Alice McNeal Professor of Anesthesiology in 1999, appointed Associate Dean for Postdoctoral Education in 2001, Senior Associate Dean of the Graduate School and Assistant Provost of Research in 2002, Acting Associate Provost for Research in December of 2002 and Acting Vice President of UAB in July 2003. He currently serves as the Vice Chair for Research of the Department of Anesthesiology and as the Director of the School of Medicine Pulmonary Injury and Repair Center.
He has been continuously funded by NIH since 1978 and received a Career Investigator Award by the American Lung Association (1987-1992), a NIH MERIT Award (1997-2007), a Recognition Award for Scientific Accomplishment by the American Thoracic Society (2002), and various awards for teaching from the University of Alabama at Birmingham including the Joint Health Sciences Presidential Teaching Award (1997), Argus Society Award for Instructional Excellence (Best Instructor, First Year Medical Class; 1997, 1998, 2001) and the Caduceus award for Best Basic Science Professor by the 2004 School of Medicine Class. In 2010 he received an Honorary Doctor of Science from the University of Thessaly, Larisa, Greece. He organized (in collaboration with Dr. Iasha Sznajder; Northwerstern University) two Advanced Study Institutes on acute lung injury (sponsored Scientific Affairs Division of NATO; 1997 and 2000) in Corfu Greece; recently he was the Codirector (along with Dr. Lester Kobzik, Harvard School of Public Health) of two workshops on Environmental Lung Disease: Environmental Chemical Threats and Lung Injury (Limassol, Cyprus, 2009-2010).
Dr. Matalon served as Associate Editor of News in Physiological Sciences (1997-2003) and Associate Editor and Deputy Editor of the American Journal of Respiratory Cell and Molecular Biology (2003-2011). He has been in the Editorial Board of the AJP-Lung since 1994 and a member of the American Physiological Society since 1975. Current research interests include redox modulation of lung ion channels and implications on lung fluid balance, viral induced injury to the mammalian alveolar epithelium and developing countermeasures against oxidant gas injury to mammalian lungs. He has trained a large number of fellows who are currently independent investigators and continues to be involved in day to day experimental design, data analysis, writing grants and manuscripts, training graduate students, and teaching pulmonary physiology to professional students and residents.