Mechanisms of Exercise-Induced Amelioration of Cardiovascular Disease

Editor in Chief Dr. Irving Zucker and Guest Editor Dr. Timothy Musch, along with the editorial team of AJP-Heart and Circulatory Physiology, invite submission of original research articles related to the mechanisms by which acute exercise and exercise training mediate changes in cardiovascular function in disease. A large and growing body of literature now show beneficial effects of exercise training in diverse cardiovascular disease states such as chronic heart failure, hypertension and arrhythmias. Virtually every organ system is impacted by exercise training. Clinical studies have also shown an impact of exercise training on survival. While there are many phenomenological studies in this area the precise mechanisms by which exercise training evokes multi-organ effects is not completely understood. Therefore, the Journal invites papers in this area. Studies uncovering the molecular, cellular or organ level physiological and pathophysiological mechanisms along with integrative and translational approaches by which exercise provides beneficial effects in cardiovascular disease will be relevant to this call. 

We will consider both original research articles and review articles. For review articles only, authors should email the editorial office ( a pre-submission inquiry including a working title, author and affiliation list, abstract and brief outline of the content for approval by the editors.   

All manuscripts accepted from this Call for Papers will be included in a unique online article collection to further highlight the importance of this topic. The article collection will also include specially commissioned Review articles on the topic.

All manuscripts should be submitted online at

During the online submission process, under the "Keywords & Special Sections" tab, please use the "Category" drop-down menu and select “Call for Papers: Mechanisms of Exercise-Induced Amelioration of Cardiovascular Disease."

Manuscripts will undergo normal peer review as they are received. Accepted manuscripts will be published online as they are accepted. Articles published from this Call for Papers will be highlighted with a special “Call for Papers” banner on the article PDF, as well as inclusion in the “Call for Papers: Mechanisms Exercise-Induced Amelioration of Cardiovascular Disease” online article collection at time of publication.

Manuscripts must be submitted by July 1, 2017 to be eligible for inclusion in this Call for Papers. If you have any questions please contact Kara Hansell Keehan, Executive Editor, via email at