» Themes

2011	Themes in Fibrosis and Gastrointestinal Inflammation
2008	The Adventures of Sonic Hedgehog in Development and Repair Endocannabinoids and Liver Disease
2007	Role of NKT Cells in the Digestive System Regulation of Triglyceride Metabolism Development and Physiological Regulation of Intestinal Lipid Absorption TLRs in the Gut
2006	Mechanisms of Liver Injury Role of Epithelial Cells in Initiation and Propagation of Intestinal Inflammation Differentiation of the Gastric Mucosa Lipid Metabolism and Liver Inflammation Taste Receptors in the Gastrointestinal Tract
2005	Iron Imports Gastrointestinal Stem Cells Epithelial Cells and Their Neighbors Events at the Host-Microbial Interface of the Gastrointestinal Tract Signal-Transduction Pathways that Regulate Visceral Smooth Muscle Function Physiological Basis for Novel Drug Therapies Used to Treat the Inflammatory Bowel Diseases
2004	Recent Events in Alcoholic Liver Disease Inflammation and Cancer Gastrointestinal Satiety Signals
2003	The Future of GI and Liver Research: Editorial Perspectives Bile Acid Regulation of Hepatic Physiology
2002	Musings on the Wanderer: What's New in Our Understanding of Vago-Vagal Reflexes? Aging and Neural Control of the GI Tract Epithelial Cell Cytoskeleton and Intracellular Trafficking Nuclear Receptors Cutting-Edge Technology
2001	Nonalcoholic Steatosis and Steatohepatitis Physiology and Pathophysiology of the Interstitial Cells of Cajal: From Bench To Bedside Receptors and Transmission in the Brain-Gut Axis: Potential for Novel Therapies Microbes and Microbial Toxins: Paradigms for Microbial-Mucosal Interactions
2000	Stress and the Gastrointestinal Tract Molecular Physiology and Pathophysiology of Tight Junctions Fibrogenesis Pathobiology of Visceral Pain: Molecular Mechanisms and Therapeutic Implications
1999	Nutrient Tasting and Signaling Mechanisms in the Gut Lessons From Genetically Engineered Animal Models Mucosal Immunity and Inflammation Nitric Oxide
1998	Genetic Disorders of Membrane Transport Mechanisms of Hepatic Toxicity Neural Injury, Repair, and Adaptation in the GI Tract G Protein-Coupled Receptors in Gastrointestinal Physiology Current Concepts in Mucosal Immunity
1997	Cell Adhesion and Migration Epithelial Cell Growth and Differentiation

Themes in Fibrosis and Gastrointestinal Inflammation

Themes in Fibrosis and Gastrointestinal Inflammation.
Claudio Fiocchi and P. Kay Lund.
Am J Physiol Gastrointest Liver Physiol 300: G677-G683. First published March 17, 2011; doi: 10.1152/ajpgi.00104.2011.

Intestinal myofibroblasts: targets for stem cell therapy.
R. C. Mifflin, I. V. Pinchuk, J. I. Saada, and D. W. Powell.
Am J Physiol Gastrointest Liver Physiol 300: G684-G696. First published January 20, 2011; doi:10.1152/ajpgi.00474.2010.

Obesity, diabetes mellitus, and liver fibrosis.
Dian J. Chiang, Michele T. Pritchard, and Laura E. Nagy.
Am J Physiol Gastrointest Liver Physiol 300: G697-G702. First published February 24, 2011; doi:10.1152/ajpgi.00426.2010.

Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention.
Jeroni Luna, Maria Carme Masamunt, Ian Craig Lawrance, and Miquel Sans.
Am J Physiol Gastrointest Liver Physiol 300: G703-G708. First published January 13, 2011; doi:10.1152/ajpgi.00504.2010.

Therapeutic targets in liver fibrosis.
Jonathan A. Fallowfield.
Am J Physiol Gastrointest Liver Physiol 300: G709-G715. First published January 13, 2011; doi:10.1152/ajpgi.00451.2010.

Immune and nonimmune components orchestrate the pathogenesis of inflammatory bowel disease.
Silvio Danese.
Am J Physiol Gastrointest Liver Physiol 300: G716-G722. First published January 13, 2011; doi:10.1152/ajpgi.00472.2010.

Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages.
Luke Barron and Thomas A. Wynn.
Am J Physiol Gastrointest Liver Physiol 300: G723-G728; published ahead of print February 3, 2011; doi:10.1152/ajpgi.00414.2010.

Animal models for the study of liver fibrosis: new insights from knockout mouse models
Hiromitsu Hayashi and Takao Sakai
Am J Physiol Gastrointest Liver Physiol 300: G729-G738. First published February 24, 2011; doi:10.1152/ajpgi.00013.2011.

The Adventures of Sonic Hedgehog in Development and Repair

1. Hedgehog signaling in gastrointestinal development and disease.
   Caroline A. Parkin and Philip W. Ingham.
   Am J Physiol Gastrointest Liver Physiol 294: G363-G367, 2008. First published December 6, 2007; doi:10.1152/ajpgi.00457.2007.
2. Sonic hedgehog and liver development, inflammation, and cancer.
   Alessia Omenetti and Anna Mae Diehl.
   Am J Physiol Gastrointest Liver Physiol 294: G595-G598, 2008. First published January 24, 2008; doi:10.1152/ajpgi.00543.2007.
3. Hedgehog processing and biological activity.
   Shohreh F. Farzan, Samer Singh, Neal S. Schilling, and David J. Robbins.
   Am J Physiol Gastrointest Liver Physiol 294: G844-G849, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00564.2007.
4. Sonic hedgehog processing, secretion, and function in the stomach.
   Yana Zavros.
   Am J Physiol Gastrointest Liver Physiol 294: G1105-G1108, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00031.2008

Endocannabinoids and Liver Disease

1. Endocannabinoids and their receptors in the liver.
   A. Mallat and S. Lotersztajn.
   Am J Physiol Gastrointest Liver Physiol 294: G9-G12, 2008. First published November 1, 2007; doi:10.1152/ajpgi.00467.2007.
2. Endocannabinoids in the pathogenesis and treatment of liver fibrosis.
   Sören V. Siegmund and Robert F. Schwabe.
   Am J Physiol Gastrointest Liver Physiol 294: G357-G362, 2008. First published November 15, 2007; doi:10.1152/ajpgi.00456.2007.
3. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases.
   Pál Pacher and Bin Gao.
   Am J Physiol Gastrointest Liver Physiol 294: G850-G854, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00523.2007.
4. Endocannabinoid involvement in obesity and hepatic steatosis.
   George Kunos and Douglas Osei-Hyiaman.
   Am J Physiol Gastrointest Liver Physiol 294: G1101-G1104, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00057.2008.
5. Endocannabinoids and Liver Disease. V. Endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis.
   Leila Moezi, Seyed Ali Gaskari, and Samuel S. Lee.
   Am J Physiol Gastrointest Liver Physiol 295: G649-G653, 2008. First published August 14, 2008; doi:10.1152/ajpgi.90352.2008.

Role of NKT Cells in the Digestive System

1. Invariant NKT cells and liver diseases: is there strength in numbers?
   Maureen N. Ajuebor.
   Am J Physiol Gastrointest Liver Physiol 293: G651-G656, 2007. First published July 12, 2007; doi:10.1152/ajpgi.00298.2007.
2. NKT cells and diabetes.
   Lan Wu and Luc Van Kaer.
   Am J Physiol Gastrointest Liver Physiol 293: G919-G922, 2007. First published June 28, 2007; doi:10.1152/ajpgi.00242.2007.
3. Role of NKT cells in intestinal immunity.
   Sebastian Zeissig, Arthur Kaser, Stephanie K. Dougan, Edward E. S. Nieuwenhuis, and Richard S. Blumberg.
   Am J Physiol Gastrointest Liver Physiol 293: G1101-G1105, 2007. First published August 23, 2007; doi:10.1152/ajpgi.00342.2007.
4. The role of canonical natural killer T cells in mucosal immunity and inflammation.
   Gerhard Wingender and Mitchell Kronenberg.
   Am J Physiol Gastrointest Liver Physiol 294: G1-G8, 2008. First published October 18, 2007; doi:10.1152/ajpgi.00437.2007.

Regulation of Triglyceride Metabolism

1. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT".
   Aaron Turkish and Stephen L. Sturley.
   Am J Physiol Gastrointest Liver Physiol 292: G953-G957, 2007. First published November 9, 2006; doi:10.1152/ajpgi.00509.2006.
2. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action.
   Maria R. Gonzalez-Baró, Tal M. Lewin, and Rosalind A. Coleman.
   Am J Physiol Gastrointest Liver Physiol 292: G1195-G1199, 2007. First published December 7, 2006; doi:10.1152/ajpgi.00553.2006.
3. Emerging role of lipid droplet protein ADFP in health and disease.
   Benny Hung-Junn Chang and Lawrence Chan.
   Am J Physiol Gastrointest Liver Physiol 292: G1465-G1468, 2007. First published December 28, 2006; doi:10.1152/ajpgi.00566.2006.
4. Hormonal regulation of lipolysis in adipose tissue.
   Kathy Jaworski, Eszter Sarkadi-Nagy, Robin E. Duncan, Maryam Ahmadian, and Hei Sook Sul.
   Am J Physiol Gastrointest Liver Physiol 293: G1-G4, 2007. First published January 11, 2007; doi:10.1152/ajpgi.00554.2006.

Development and Physiological Regulation of Intestinal Lipid Absorption

1. Development of intestinal lipid absorption: cellular events in chylomicron assembly and secretion.
   Dennis D. Black.
   Am J Physiol Gastrointest Liver Physiol 293: G519-G524, 2007. First published May 10, 2007; doi:10.1152/ajpgi.00189.2007.
2. Dietary lipid absorption, complex lipid synthesis, and the intracellular packaging and secretion of chylomicrons.
   Charles M. Mansbach, II and Fred Gorelick.
   Am J Physiol Gastrointest Liver Physiol 293: G645-G650, 2007. First published July 12, 2007; doi:10.1152/ajpgi.00299.2007.
3. Intestinal transporters and cholesterol absorption.
   David Y. Hui, Eric D. Labonté, and Philip N. Howles.
   Am J Physiol Gastrointest Liver Physiol 294: G839-G843, 2008. First published February 14, 2008; doi:10.1152/ajpgi.00061.2008.

    

TLRs in the Gut

1. The role of TLRs/Nods in intestinal development and homeostasis.
   Ian R. Sanderson and W. Allan Walker.
   Am J Physiol Gastrointest Liver Physiol 292: G6-G10, 2007. First published July 13, 2006; doi:10.1152/ajpgi.00275.2006.
2. Flagellin-induced inflammation and antiapoptosis.
   Andrew S. Neish.
   Am J Physiol Gastrointest Liver Physiol 292: G462-G466, 2007. First published November 2, 2006; doi:10.1152/ajpgi.00274.2006.
3. Immune responses to flagellin in Crohn's disease: good, bad, or irrelevant?
   Andrew T. Gewirtz.
   Am J Physiol Gastrointest Liver Physiol 292: G706-G710, 2007. First published October 12, 2006; doi:10.1152/ajpgi.00347.2006. 
4. Negative regulation of Toll-like receptors and intestinal homeostasis: addition by subtraction.
   Oren Shibolet and Daniel K. Podolsky.
   Am J Physiol Gastrointest Liver Physiol 292: G1469-G1473, 2007; doi:10.1152/ajpgi.00531.2006

Mechanisms of Liver Injury

1. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways.
   Robert F. Schwabe and David A. Brenner.
   Am J Physiol Gastrointest Liver Physiol 290: G583-G589, 2006; doi:10.1152/ajpgi.00422.2005.
2. Oxidative stress in the pathogenesis of hepatitis C virus.
   Jinah Choi and J.-H. James Ou.
   Am J Physiol Gastrointest Liver Physiol 290: G847-G851, 2006; doi:10.1152/ajpgi.00522.2005.
3. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions.
   Hartmut Jaeschke.
   Am J Physiol Gastrointest Liver Physiol 290: G1083-G1088, 2006; doi:10.1152/ajpgi.00568.2005.
4. Role of glutathione redox status in liver injury.
   Derick Han, Naoko Hanawa, Behnam Saberi, and Neil Kaplowitz.
   Am J Physiol Gastrointest Liver Physiol 291: G1-G7, 2006. First published February 23, 2006; doi:10.1152/ajpgi.00001.2006.

Role of Epithelial Cells in Initiation and Propagation of Intestinal Inflammation

1. Eliminating the static: tight junction dynamics exposed.
   Le Shen and Jerrold R. Turner.
   Am J Physiol Gastrointest Liver Physiol 290: G577-G582, 2006; doi:10.1152/ajpgi.00439.2005.

Differentiation of the Gastric Mucosa

1. Role of histamine in control of function and integrity of oxyntic mucosa: understanding gastric physiology through disruption of targeted genes.
   Duan Chen, Takeshi Aihara, Chun-Mei Zhao, Rolf Håkanson, and Susumu Okabe.
   Am J Physiol Gastrointest Liver Physiol 291: G539-G544, 2006; doi:10.1152/ajpgi.00178.2006.
2. Role of gastrin in gastric epithelial cell proliferation and maturation.
   Renu N. Jain and Linda C. Samuelson.
   Am J Physiol Gastrointest Liver Physiol 291: G762-G765, 2006; doi:10.1152/ajpgi.00172.2006.
3. Animal models of oxyntic atrophy and metaplasia.
   James R. Goldenring and Sachiyo Nomura.
   Am J Physiol Gastrointest Liver Physiol 291: G999-G1004, 2006; doi:10.1152/ajpgi.00187.2006.
4. Role of trefoil peptides and IL-6 cytokine family signaling in gastric homeostasis.
   A. S. Giraud, C. Jackson, T. R. Menheniott, and L. M. Judd.
   Am J Physiol Gastrointest Liver Physiol 292: G1-G5, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00382.2006.

Lipid Metabolism and Liver Inflammation

1. Hepatic fatty acid uptake: possible role in steatosis.
   Michael W. Bradbury.
   Am J Physiol Gastrointest Liver Physiol 290: G194-G198, 2006; doi:10.1152/ajpgi.00413.2005.
2. Fatty liver disease and fatty acid oxidation.
   Janardan K. Reddy and M. Sambasiva Rao.
   Am J Physiol Gastrointest Liver Physiol 290: G852-G858, 2006; doi:10.1152/ajpgi.00521.2005.

Taste Receptors in the Gastrointestinal Tract

1. Bitter taste receptors and α-gustducin in the mammalian gut.
   Enrique Rozengurt.
   Am J Physiol Gastrointest Liver Physiol 291: G171-G177, 2006. First published May 18, 2006; doi:10.1152/ajpgi.00073.2006.
2. L-Amino acid sensing by calcium-sensing receptors: implications for GI physiology.
   Arthur D. Conigrave and Edward M. Brown.
   Am J Physiol Gastrointest Liver Physiol 291: G753-G761, 2006; doi:10.1152/ajpgi.00189.2006.
3. Salty and sour taste: sensing of sodium and protons by the tongue.
   John A. DeSimone and Vijay Lyall.
   Am J Physiol Gastrointest Liver Physiol 291: G1005-G1010, 2006. First published June 29, 2006; doi:10.1152/ajpgi.00235.2006. 
4. Functional implications of bitter taste receptors in gastrointestinal chemosensing.
   Catia Sternini.
   Am J Physiol Gastrointest Liver Physiol 292: G457-G461, 2007. First published November 9, 2006; doi:10.1152/ajpgi.00411.2006.
5. Acid sensing in the gastrointestinal tract.
   Peter Holzer.
   Am J Physiol Gastrointest Liver Physiol 292: G699-G705, 2007. First published November 22, 2006; doi:10.1152/ajpgi.00517.2006.

Iron Imports

1. Intestinal iron absorption and its regulation.
   David M. Frazer and Gregory J. Anderson.
   Am J Physiol Gastrointest Liver Physiol 289: G631-G635, 2005; doi:10.1152/ajpgi.00220.2005.
2. Iron uptake at the apical membrane in the intestine.
   Bryan Mackenzie and Michael D. Garrick.
   Am J Physiol Gastrointest Liver Physiol 289: G981-G986, 2005; doi:10.1152/ajpgi.00363.2005.
3. Transfer of iron from the mucosa into circulation.
   Marianne Wessling-Resnick.
   Am J Physiol Gastrointest Liver Physiol 290: G1-G6, 2006; doi:10.1152/ajpgi.00415.2005.
4. Hepcidin and regulation of body iron metabolism.
   Tomas Ganz and Elizabeta Nemeth.
   Am J Physiol Gastrointest Liver Physiol 290: G199-G203, 2006; doi:10.1152/ajpgi.00412.2005.
5. Transport of iron through the intestinal epithelium.
   Yuxiang Ma, Mary Yeh, Kwo-yih Yeh, and Jonathan Glass.
   Am J Physiol Gastrointest Liver Physiol 290: G417-G422, 2006; doi:10.1152/ajpgi.00489.2005.
6. HFE and regulation of intestinal iron absorption.
   Robert E. Fleming and Robert S. Britton.
   Am J Physiol Gastrointest Liver Physiol 290: G590-G594, 2006; doi:10.1152/ajpgi.00486.2005.

Gastrointestinal Stem Cells

1. Pancreatic stem cells.
   Bernat Soria, Francisco J. Bedoya, and Franz Martin.
   Am J Physiol Gastrointest Liver Physiol 289: G177-G180, 2005; doi:10.1152/ajpgi.00116.2005.
2. Intestinal stem cells.
   Matthew Bjerknes and Hazel Cheng.
   Am J Physiol Gastrointest Liver Physiol 289: G381-G387, 2005; doi:10.1152/ajpgi.00160.2005.
3. Emergent themes of liver stem cell biology: niche, quiescence, self-renewal, and plasticity.
   Neil D. Theise.
   Am J Physiol Gastrointest Liver Physiol 290: G189-G193, 2006; doi:10.1152/ajpgi.00041.2005.

Epithelial Cells and Their Neighbors

1. Role of intestinal myofibroblasts in development, repair, and cancer.
   D. W. Powell, P. A. Adegboyega, J. F. Di Mari, and R. C. Mifflin.
   Am J Physiol Gastrointest Liver Physiol 289: G2-G7, 2005; doi:10.1152/ajpgi.00075.2005.
2. New perspectives on efferent signaling between brain, neuroendocrine cells, and gut epithelial cells.
   Gunnar Flemström and Markus Sjöblom.
   Am J Physiol Gastrointest Liver Physiol 289: G377-G380, 2005; doi:10.1152/ajpgi.00093.2005.
3. Interactions between intraepithelial lymphocytes and neighboring epithelial cells.
   Wendy L. Havran, Julie M. Jameson, and Deborah A. Witherden.  
   Am J Physiol Gastrointest Liver Physiol 289: G627-G630, 2005; doi:10.1152/ajpgi.00224.2005.
4. Bacterial contributions to intestinal epithelial barrier integrity.
   Anisa S. Ismail and Lora V. Hooper.
   Am J Physiol Gastrointest Liver Physiol 289: G779-G784, 2005; doi:10.1152/ajpgi.00203.2005.

Events at the Host-Microbial Interface of the Gastrointestinal Tract

1. Adaptation to a microbial world: role of epithelial bactericidal/permeability-increasing protein.
   Geraldine Canny and Sean P. Colgan.
   Am J Physiol Gastrointest Liver Physiol 288: G593-G597, 2005; doi:10.1152/ajpgi.00506.2004.
2. Role of the intestinal epithelium in pathogen-induced inflammation.
   Karen L. Mumy and Beth A. McCormick.
   Am J Physiol Gastrointest Liver Physiol 288: G854-G859, 2005; doi:10.1152/ajpgi.00565.2004.
3. Cell-to-cell signaling among microbial flora, host, and pathogens: there is a whole lot of talking going on.
   Marcie B. Clarke and Vanessa Sperandio.
   Am J Physiol Gastrointest Liver Physiol 288: G1105-G1109, 2005; doi:10.1152/ajpgi.00572.2004.
4. The pathogenesis of Helicobacter pylori persistence.
   Richard M. Peek, Jr.
   Am J Physiol Gastrointest Liver Physiol 289: G8-G12, 2005; doi:10.1152/ajpgi.00086.2005.
5. Paneth cell α-defensins in intestinal host defense.
   Charles L. Bevins.
   Am J Physiol Gastrointest Liver Physiol 289: G173-G176, 2005; doi:10.1152/ajpgi.00079.2005.

Signal-Transduction Pathways that Regulate Visceral Smooth Muscle Function

1. Signal transduction in phasic (esophageal) and tonic (gastroesophageal sphincter) smooth muscles.
   Karen M. Harnett, Weibiao Cao, and Piero Biancani.
   Am J Physiol Gastrointest Liver Physiol 288: G407-G416, 2005; doi:10.1152/ajpgi.00398.2004.
2. Receptor-ion channel coupling mechanisms in gastrointestinal smooth muscle.
   Hamid I. Akbarali.
   Am J Physiol Gastrointest Liver Physiol 288: G598-G602, 2005; doi:10.1152/ajpgi.00402.2004.
3. Coupling of muscarinic receptors to signaling kinases and effector proteins in gastrointestinal smooth muscles.
   William T. Gerthoffer
   Am J Physiol Gastrointest Liver Physiol 288: G849-G853, 2005; doi:10.1152/ajpgi.00530.2004.

Physiological Basis for Novel Drug Therapies Used to Treat the Inflammatory Bowel Diseases

1. Immunology and therapeutic potential of antiadhesion molecule therapy in inflammatory bowel disease.
   Gert Van Assche and Paul Rutgeerts.
   Am J Physiol Gastrointest Liver Physiol 288: G169-G174, 2005; doi:10.1152/ajpgi.00423.2004.
2. Pathophysiological basis and prospects for probiotic therapy in inflammatory bowel disease.
   Fergus Shanahan.
   Am J Physiol Gastrointest Liver Physiol 288: G417-G421, 2005; doi:10.1152/ajpgi.00421.2004.

Recent Events in Alcoholic Liver Disease

1. Role of intestinal permeability and endotoxemia in alcoholic liver disease.
   R. K. Rao, A. Seth, and P. Sheth.
   Am J Physiol Gastrointest Liver Physiol 286: G881-G884, 2004; 10.1152/ajpgi.00006.2004.
2. Minireview: molecular mechanisms of alcoholic fatty liver.
   Min You and David W. Crabb.
   Am J Physiol Gastrointest Liver Physiol 287: G1-G6, 2004; 10.1152/ajpgi.00056.2004.
3. Role of the innate immune response in alcoholic hepatitis.
   Ian N. Hines and Michael D. Wheeler.
   Am J Physiol Gastrointest Liver Physiol 287: G310-G314, 2004; doi:10.1152/ajpgi.00094.2004.
4. Dysregulated cytokine metabolism in alcoholic liver disease.
   Craig J. McClain, Zhenyuan Song, Shirish S. Barve, Daniell B. Hill, and Ion Deaciuc.
   Am J Physiol Gastrointest Liver Physiol 287: G497-G502, 2004; doi:10.1152/ajpgi.00171.2004.
5. Effects of ethanol on liver regeneration.
   Anna Mae Diehl.
   Am J Physiol Gastrointest Liver Physiol 288: G1-G6, 2005; doi:10.1152/ajpgi.00376.2004.

Inflammation and Cancer

1. Rodent models of infectious gastrointestinal and liver cancer.
   Arlin B. Rogers and James G. Fox.
   Am J Physiol Gastrointest Liver Physiol 286: G361-G366, 2004; 10.1152/ajpgi.00499.2003.
2. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy.
   Mairi Macarthur, Georgina L. Hold, and Emad M. El-Omar.
   Am J Physiol Gastrointest Liver Physiol 286: G515-G520, 2004; 10.1152/ajpgi.00475.2003.
3. Somatostatin and the innate immune system.
   Yana Zavros, John Y. Kao, and Juanita L. Merchant.
   Am J Physiol Gastrointest Liver Physiol 286: G698-G701, 2004; 10.1152/ajpgi.00529.2003.
4. Colorectal cancer in inflammatory bowel disease: the role of inflammation.
   Steven H. Itzkowitz and Xianyang Yio.
   Am J Physiol Gastrointest Liver Physiol 287: G7-G17, 2004; 10.1152/ajpgi.00079.2004.
5. Chronic pancreatitis and pancreatic cancer.
   David C. Whitcomb.
   Am J Physiol Gastrointest Liver Physiol 287: G315-G319, 2004; doi:10.1152/ajpgi.00115.2004.

Gastrointestinal Satiety Signals

1. An overview of gastrointestinal signals that influence food intake.
   Stephen C. Woods.
   Am J Physiol Gastrointest Liver Physiol 286: G7-G13, 2004; 10.1152/ajpgi.00448.2003
2. Cholecystokinin.
   Timothy H. Moran and Kimberly P. Kinzig.
   Am J Physiol Gastrointest Liver Physiol 286: G183-G188, 2004; 10.1152/ajpgi.00434.2003.
3. Glucagon-like peptide 1, oxyntomodulin, peptide YY, and pancreatic polypeptide.
   Sarah Stanley, Katie Wynne, and Steve Bloom.
   Am J Physiol Gastrointest Liver Physiol 286: G693-G697, 2004; 10.1152/ajpgi.00536.2003.
4. Apolipoprotein A-IV.
   Patrick Tso, William Sun, and Min Liu.
   Am J Physiol Gastrointest Liver Physiol 286: G885-G890, 2004; 10.1152/ajpgi.00511.2003.

The Future of GI and Liver Research: Editorial Perspectives

1. Visions of epithelial research.
   Marshall H. Montrose.
   Am J Physiol Gastrointest Liver Physiol 284: G547-G550, 2003; 10.1152/ajpgi.00547.2002.
2. Modulating leukocyte recruitment to splanchnic organs to reduce inflammation.
   Claudine S. Bonder and Paul Kubes.
   Am J Physiol Gastrointest Liver Physiol 284: G729-G733, 2003; 10.1152/ajpgi.00023.2003.
3. JNK/AP-1 regulation of hepatocyte death.
   Mark J. Czaja.
   Am J Physiol Gastrointest Liver Physiol 284: G875-G879, 2003; 10.1152/ajpgi.00549.2002.
4. Visceral afferents: an update.
   Helen E. Raybould.
   Am J Physiol Gastrointest Liver Physiol 284: G880-G882, 2003; 10.1152/ajpgi.00123.2003.

Bile Acid Regulation of Hepatic Physiology

1. Hepatocyte transport of bile acids.
   Allan W. Wolkoff and David E. Cohen.
   Am J Physiol Gastrointest Liver Physiol 284: G175-G179, 2003; 10.1152/ajpgi.00409.2002.
2. Bile acids and nuclear receptors.
   John Y. L. Chiang.
   Am J Physiol Gastrointest Liver Physiol 284: G349-G356, 2003; 10.1152/ajpgi.00417.2002.
3. Regulation of bile acid synthesis: past progress and future challenges.
   Michael Fuchs.
   Am J Physiol Gastrointest Liver Physiol 284: G551-G557, 2003; 10.1152/ajpgi.00468.2002.
4. Bile acids and death receptors.
   Hajime Higuchi and Gregory J. Gores.
   Am J Physiol Gastrointest Liver Physiol 284: G734-G738, 2003; 10.1152/ajpgi.00491.2002.

Musings on the Wanderer: What's New in Our Understanding of Vago-Vagal Reflexes?

1. Morphology and topography of vagal afferents innervating the GI tract
   Terry L. Powley and Robert J. Phillips.
   Am J Physiol Gastrointest Liver Physiol 283: G1217-G1225, 2002; 10.1152/ajpgi.00249.2002.
2. Integration of afferent signaling from the viscera by the nodose ganglia.
   Kirsteen N. Browning and David Mendelowitz.
   Am J Physiol Gastrointest Liver Physiol 284: G8-G14, 2003; 10.1152/ajpgi.00322.2002.
3. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach.
   R. Alberto Travagli, Gerlinda E. Hermann, Kirsteen N. Browning, and Richard C. Rogers.
   Am J Physiol Gastrointest Liver Physiol 284: G180-G187, 2003; 10.1152/ajpgi.00413.2002.
4. Current concepts of vagal efferent projections to the gut.
   Howard Y. Chang, Hiroshi Mashimo, and Raj K. Goyal.
   Am J Physiol Gastrointest Liver Physiol 284: G357-G366, 2003; 10.1152/ajpgi.00478.2002.
5. Remodeling of vagus and enteric neural circuitry after vagal injury.
   Ying Li and Chung Owyang.
   Am J Physiol Gastrointest Liver Physiol 285: G461-G469, 2003; 10.1152/ajpgi.00119.2003.

Aging and Neural Control of the GI Tract

1. Age-related changes in the enteric nervous system.
   Paul R. Wade.
   Am J Physiol Gastrointest Liver Physiol 283: G489-G495, 2002; 10.1152/ajpgi.00091.2002.
2. Neural control of the aging gut: can an old dog learn new tricks?
   Karen E. Hall.
   Am J Physiol Gastrointest Liver Physiol 283: G827-G832, 2002; 10.1152/ajpgi.00162.2002
3. Senescent enteric nervous system: lessons from extraintestinal sites and nonmammalian species.
   John W. Wiley.
   Am J Physiol Gastrointest Liver Physiol 283: G1020-G1026, 2002; 10.1152/ajpgi.00224.2002.
4. Clinical and physiological aspects of gastrointestinal motility and aging.
   William C. Orr and C. L. Chen.
   Am J Physiol Gastrointest Liver Physiol 283: G1226-G1231, 2002; 10.1152/ajpgi.00276.2002.
5. Aging and gastrointestinal smooth muscle: from signal transduction to contractile proteins.
   Khalil N. Bitar.
   Am J Physiol Gastrointest Liver Physiol 284: G1-G7, 2003; 10.1152/ajpgi.00264.2002.

Epithelial Cell Cytoskeleton and Intracellular Trafficking

1. Shiga toxin B-subunit system: retrograde transport, intracellular vectorization, and more.
   Ludger Johannes.
   Am J Physiol Gastrointest Liver Physiol 283: G1-G7, 2002; 10.1152/ajpgi.00088.2002.
2. Intestinal epithelial cell exosomes: perspectives on their structure and function.
   Guillaume van Niel and Martine Heyman.
   Am J Physiol Gastrointest Liver Physiol 283: G251-G255, 2002; 10.1152/ajpgi.00102.2002.
3. How is villin involved in the actin cytoskeleton dynamics in intestinal cells?
   Rafika Athman, Daniel Louvard, and Sylvie Robine.
   Am J Physiol Gastrointest Liver Physiol 283: G496-G502, 2002; 10.1152/ajpgi.00207.2002.
4. Polarized compartmentalization of antigen processing and Toll-like receptor signaling in intestinal epithelial cells.
   Robert M. Hershberg.
   Am J Physiol Gastrointest Liver Physiol 283: G833-G839, 2002; 10.1152/ajpgi.00208.2002.
5. Confluence of membrane trafficking and motility in epithelial cell models.
   James E. Casanova.
   Am J Physiol Gastrointest Liver Physiol 283: G1015-G1019, 2002; 10.1152/ajpgi.00255.2002.

Nuclear Receptors

1. PPARγ in the gastrointestinal tract: gain or pain?
   Johan Auwerx.
   Am J Physiol Gastrointest Liver Physiol 282: G581-G585, 2002; 10.1152/ajpgi.00508.2001.
2. Intestinal corticosteroid receptors.
   Karen E. Sheppard.
   Am J Physiol Gastrointest Liver Physiol 282: G742-G746, 2002; 10.1152/ajpgi.00531.2001.
3. Nuclear receptors and bile acid homeostasis.
   Bryan Goodwin and Steven A. Kliewer.
   Am J Physiol Gastrointest Liver Physiol 282: G926-G931, 2002; 10.1152/ajpgi.00044.2002.

Cutting-Edge Technology

1. Global gene expression profiling using DNA microarrays.
   Mayi Arcellana-Panlilio and Stephen M. Robbins.
   Am J Physiol Gastrointest Liver Physiol 282: G397-G402, 2002; 10.1152/ajpgi.00519.2001.
2. Proteomics: core technologies and applications in physiology.
   Frank A. Witzmann and Junyu Li.
   Am J Physiol Gastrointest Liver Physiol 282: G735-G741, 2002; 10.1152/ajpgi.00510.2001.
3. Imaging and the gastrointestinal tract: mapping the human enteric nervous system.
   Michael Schemann, Klaus Michel, Saskia Peters, Stephan C. Bischoff, and Michel Neunlist.
   Am J Physiol Gastrointest Liver Physiol 282: G919-G925, 2002; 10.1152/ajpgi.00043.2002.
4. Genomic engineering for studies of the gastrointestinal tract in mice.
   Daniel C. Bullard and Casey T. Weaver.
   Am J Physiol Gastrointest Liver Physiol 283: G1232-G1237, 2002; 10.1152/ajpgi.00035.2002.

Nonalcoholic Steatosis and Steatohepatitis

1. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription.
   Steven D. Clarke.
   Am J Physiol Gastrointest Liver Physiol 281: G865-G869, 2001.
2. Cytochrome P-450 enzymes and oxidative stress.
   Graham Robertson, Isabelle Leclercq, and Geoffrey C. Farrell.
   Am J Physiol Gastrointest Liver Physiol 281: G1135-G1139, 2001.
3. Peroxisomal β-oxidation, PPARα, and steatohepatitis.
   Janardan K. Reddy.
   Am J Physiol Gastrointest Liver Physiol 281: G1333-G1339, 2001.
4. Nonalcoholic fatty liver disease abnormalities in macrophage function and cytokines.
   Anna Mae Diehl.
   Am J Physiol Gastrointest Liver Physiol 282: G1-G5, 2002; 10.1152/ajpgi.00384.2001.
5. Mitochondrial dysfunction in steatohepatitis.
   Dominique Pessayre, Abdellah Mansouri, and Bernard Fromenty.
   Am J Physiol Gastrointest Liver Physiol 282: G193-G199, 2002; 10.1152/ajpgi.00426.2001.

Physiology and Pathophysiology of the Interstitial Cells of Cajal: From Bench To Bedside

1. Functional development and plasticity of interstitial cells of Cajal networks.
   Sean M. Ward and Kenton M. Sanders.
   Am J Physiol Gastrointest Liver Physiol 281: G602-G611, 2001.
2. Gastric motility: lessons from mutant mice on slow waves and innervation.
   Jan D. Huizinga.
   Am J Physiol Gastrointest Liver Physiol 281: G1129-G1134, 2001.
3. Interaction of interstitial cells of Cajal with neuromediators: an interim assessment.
   E. E. Daniel.
   Am J Physiol Gastrointest Liver Physiol 281: G1329-G1332, 2001.
4. Genetic and animal models of GI motility disorders caused by loss of interstitial cells of Cajal.
   Kenton M. Sanders, Tamás Ördög, and Sean M. Ward.
   Am J Physiol Gastrointest Liver Physiol 282: G747-G756, 2002; 10.1152/ajpgi.00362.2001.
5. Pathogenesis and therapeutic approaches to human gastric dysrhythmias.
   Chung Owyang and William L. Hasler.
   Am J Physiol Gastrointest Liver Physiol 283: G8-G15, 2002; 10.1152/ajpgi.00095.2002.

Receptors and Transmission in the Brain-Gut Axis: Potential for Novel Therapies

1. Receptors on visceral afferents.
   Anthony J. Kirkup, Alan M. Brunsden, and David Grundy.
   Am J Physiol Gastrointest Liver Physiol 280: G787-G794, 2001.
2. Excitatory amino acid receptors in the brain-gut axis.
   Pamela J. Hornby.
   Am J Physiol Gastrointest Liver Physiol 280: G1055-G1060, 2001.
3. μ-Opioid receptors in the enteric nervous system.
   Catia Sternini.
   Am J Physiol Gastrointest Liver Physiol 281: G8-G15, 2001.
4. GABA_B receptors in the brain-gastroesophageal axis.
   L. Ashley Blackshaw.
   Am J Physiol Gastrointest Liver Physiol 281: G311-G315, 2001.
5. Fast and slow extrinsic modulation of dorsal vagal complex circuits.
   R. Alberto Travagli and Richard C. Rogers.
   Am J Physiol Gastrointest Liver Physiol 281: G595-G601, 2001.

Microbes and Microbial Toxins: Paradigms for Microbial-Mucosal Interactions

1. Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogen Giardia lamblia.
   Lars Eckmann and Frances D. Gillin.
   Am J Physiol Gastrointest Liver Physiol 280: G1-G6, 2001.
2. The integrated response of the intestine to Clostridium difficile toxins.
   Charalabos Pothoulakis and J. Thomas Lamont.
   Am J Physiol Gastrointest Liver Physiol 280: G178-G183, 2001.
3. Shigellosis: from symptoms to molecular pathogenesis.
   Philippe J. Sansonetti.
   Am J Physiol Gastrointest Liver Physiol 280: G319-G323, 2001.
4. Helicobacter pylori strain-specific activation of signal transduction cascades related to gastric inflammation.
   Richard M. Peek Jr.
   Am J Physiol Gastrointest Liver Physiol 280: G525-G530, 2001.
5. Cholera: invasion of the intestinal epithelial barrier by a stably folded protein toxin.
   Wayne I. Lencer.
   Am J Physiol Gastrointest Liver Physiol 280: G781-G786, 2001.
6. Entamoeba histolytica: parasite-host interactions.
   Samuel L. Stanley Jr. and Sharon L. Reed.
   Am J Physiol Gastrointest Liver Physiol 280: G1049-G1054, 2001.
7. Enteropathogenic Escherichia coli: physiological alterations from an extracellular position.
   Gail Hecht.
   Am J Physiol Gastrointest Liver Physiol 281: G1-G7, 2001.
8. Pathological consequences of rotavirus infection and its enterotoxin.
   Andrew P. Morris and Mary K. Estes.
   Am J Physiol Gastrointest Liver Physiol 281: G303-G310, 2001.

Stress and the Gastrointestinal Tract

1. Stress and hepatic inflammation.
   Mark G. Swain.
   Am J Physiol Gastrointest Liver Physiol 279: G1135-G1138, 2000.
2. Stress and intestinal barrier function.
   Johan D. Söderholm and Mary H. Perdue.
   Am J Physiol Gastrointest Liver Physiol 280: G7-G13, 2001.
3. Stress-related alterations of gut motor function: role of brain corticotropin-releasing factor receptors.
   Yvette Taché, Vicente Martinez, Mulugeta Million, and Lixin Wang.
   Am J Physiol Gastrointest Liver Physiol 280: G173-G177, 2001.
4. Modulation of intestinal inflammation by stress: basic mechanisms and clinical relevance.
   Stephen M. Collins.
   Am J Physiol Gastrointest Liver Physiol 280: G315-G318, 2001.
5. Stress and irritable bowel syndrome.
   Emeran A. Mayer, Bruce D. Naliboff, Lin Chang, and Santosh V. Coutinho.
   Am J Physiol Gastrointest Liver Physiol 280: G519-G524, 2001.

Molecular Physiology and Pathophysiology of Tight Junctions

1. Tight junction structure and function: lessons from mutant animals and proteins.
   Laura L. Mitic, Christina M. Van Itallie, and James M. Anderson.
   Am J Physiol Gastrointest Liver Physiol 279: G250-G254, 2000.
2. Biogenesis of tight junctions and epithelial polarity.
   M. Cereijido, L. Shoshani, and R. G. Contreras.
   Am J Physiol Gastrointest Liver Physiol 279: G477-G482, 2000.
3. Tight junction regulation by intracellular messengers: differences in response within and between epithelia.
   Jurgen Karczewski and Jack Groot.
   Am J Physiol Gastrointest Liver Physiol 279: G660-G665, 2000.
4. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells.
   A. Nusrat, J. R. Turner, and J. L. Madara.
   Am J Physiol Gastrointest Liver Physiol 279: G851-G857, 2000.
5. Assault of the tight junction by enteric pathogens.
   Cynthia L. Sears.
   Am J Physiol Gastrointest Liver Physiol 279: G1129-G1134, 2000.

Fibrogenesis

1. New insights into hepatic stellate cell activation: the simple becomes complex.
   Francis J. Eng and Scott L. Friedman.
   Am J Physiol Gastrointest Liver Physiol 279: G7-G11, 2000.
2. Metalloproteinases and their inhibitors in liver fibrosis
   Michael J. P. Arthur.
   Am J Physiol Gastrointest Liver Physiol 279: G245-G249, 2000.
3. Posttranscriptional regulation of type I collagen.
   J. N. Lindquist, W. F. Marzluff, and B. Stefanovic.
   Am J Physiol Gastrointest Liver Physiol 279: G471-G476, 2000.
4. Fibrosis and inflammatory bowel disease: cellular mediators and animal models.
   Jolanta B. Pucilowska, Kristen L. Williams, and P. Kay Lund.
   Am J Physiol Gastrointest Liver Physiol 279: G653-G659, 2000.
5. TGF-β signaling pathways.
   Rebecca G. Wells.
   Am J Physiol Gastrointest Liver Physiol 279: G845-G850, 2000.

Pathobiology of Visceral Pain: Molecular Mechanisms and Therapeutic Implications

1. Cellular and molecular biology of sodium channel β-subunits: therapeutic implications for pain?
   Lori L. Isom.
   Am J Physiol Gastrointest Liver Physiol 278: G349-G353, 2000.
2. Genetic approaches to pain therapy.
   John N. Wood.
   Am J Physiol Gastrointest Liver Physiol 278: G507-G512, 2000.
3. Visceral afferent pathways: a source of new therapeutic targets for abdominal pain.
   Lionel Buéno, Jean Fioramonti, and Rafael Garcia-Villar.
   Am J Physiol Gastrointest Liver Physiol 278: G670-G676, 2000.
4. Visceral afferent contributions to the pathobiology of visceral pain.
   G. F. Gebhart.
   Am J Physiol Gastrointest Liver Physiol 278: G834-G838, 2000.
5. Central nervous system processing of somatic and visceral sensory signals.
   Uri Ladabaum, Satoshi Minoshima, and Chung Owyang.
   Am J Physiol Gastrointest Liver Physiol 279: G1-G6, 2000.

Nutrient Tasting and Signaling Mechanisms in the Gut

1. Sensing of lipid by the intestinal mucosa.
   Helen E. Raybould.
   Am J Physiol Gastrointest Liver Physiol 277: G751-G755, 1999.
2. The intestine as a sensory organ: neural, endocrine, and immune responses.
   John B. Furness, Wolfgang A. A. Kunze, and Nadine Clerc.
   Am J Physiol Gastrointest Liver Physiol 277: G922-G928, 1999.
3. Endocrine cell recognition of luminal nutrients
   Alison M. J. Buchan.
   Am J Physiol Gastrointest Liver Physiol 277: G1103-G1107, 1999.
4. There is more to taste than meets the tongue.
   Donald B. Katz, Miguel A. L. Nicolelis, and S. A. Simon.
   Am J Physiol Gastrointest Liver Physiol 278: G6-G9, 2000.
5. Mechanisms of immunologic sensation of intestinal contents.
   Fergus Shanahan.
   Am J Physiol Gastrointest Liver Physiol 278: G191-G196, 2000.

Lessons From Genetically Engineered Animal Models

1. Physiological studies with gastrin in transgenic mice.
   Timothy C. Wang and Graham J. Dockray.
   Am J Physiol Gastrointest Liver Physiol 277: G6-G11, 1999.
2. Disorders of enteric neuronal development: insights from transgenic mice.
   Michael D. Gershon.
   Am J Physiol Gastrointest Liver Physiol 277: G262-G267, 1999.
3. Lessons learned from gastrin gene deletion in mice.
   Karen L. Hinkle and Linda C. Samuelson.
   Am J Physiol Gastrointest Liver Physiol 277: G500-G505, 1999.
4. Nitric oxide synthase gene knockout mice.
   Hiroshi Mashimo and Raj K. Goyal.
   Am J Physiol Gastrointest Liver Physiol 277: G745-G750, 1999.
5. Knocking out genes to study liver regeneration: present and future.
   Nelson Fausto.
   Am J Physiol Gastrointest Liver Physiol 277: G917-G921, 1999.
6. Liver repopulation systems and study of pathophysiological mechanisms in animals.
   Sanjeev Gupta and Charles E. Rogler.
   Am J Physiol Gastrointest Liver Physiol 277: G1097-G1102, 1999.
7. Apoptosis in intestinal epithelium: lessons from transgenic and knockout mice.
   Alastair J. M. Watson and D. Mark Pritchard.
   Am J Physiol Gastrointest Liver Physiol 278: G1-G5, 2000.
8. Absorption and secretion of ions in the gastrointestinal tract.
   Gary E. Shull, Marian L. Miller, and Patrick J. Schultheis.
   Am J Physiol Gastrointest Liver Physiol 278: G185-G190, 2000.
9. Mast cell-deficient mice and intestinal biology.
   Barry K. Wershil.
   Am J Physiol Gastrointest Liver Physiol 278: G343-G348, 2000.
10. Trefoil peptide and EGF receptor/ligand transgenic mice.
    Andrew S. Giraud.
    Am J Physiol Gastrointest Liver Physiol 278: G501-G506, 2000.
11. Novel mouse models to study pathogenic mechanisms of Crohn's disease.
    Theresa T. Pizarro, Kristen O. Arseneau, and Fabio Cominelli.
    Am J Physiol Gastrointest Liver Physiol 278: G665-G669, 2000.
12. IL-10-deficient (IL-10^-/-) mice and intestinal inflammation.
    Donna M. Rennick and Madeline M. Fort.
    Am J Physiol Gastrointest Liver Physiol 278: G829-G833, 2000.

Mucosal Immunity and Inflammation

1. Mucosal dendritic cells: their specialized role in initiating T cell responses.
   Akiko Iwasaki and Brian L. Kelsall.
   Am J Physiol Gastrointest Liver Physiol 276: G1074-G1078, 1999.
2. The yin and yang of T cells in intestinal inflammation: pathogenic and protective roles in a mouse colitis model.
   Hilde de Winter, Hilde Cheroutre, and Mitchell Kronenberg.
   Am J Physiol Gastrointest Liver Physiol 276: G1317-G1321, 1999.
3. The mucosal antigen barrier: cross talk with mucosal cytokines.
   Mary H. Perdue.
   Am J Physiol Gastrointest Liver Physiol 277: G1-G5, 1999.
4. Paneth cell antimicrobial peptides and the biology of the mucosal barrier.
   Andre J. Ouellette.
   Am J Physiol Gastrointest Liver Physiol 277: G257-G261, 1999.
5. Innate mechanisms of mucosal defense and repair: the best offense is a good defense.
   Daniel K. Podolsky.
   Am J Physiol Gastrointest Liver Physiol 277: G495-G499, 1999.

Nitric Oxide

1. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation.
   Matthew B. Grisham, David Jourd'Heuil, and David A. Wink.
   Am J Physiol Gastrointest Liver Physiol 276: G315-G321, 1999.
2. Nitric oxide protects in intestinal inflammation.
   Allan M. Lefer and David J. Lefer.
   Am J Physiol Gastrointest Liver Physiol 276: G572-G575, 1999.
3. A molecular prelude to intestinal inflammation.
   Mark J. S. Miller and Manuel Sandoval.
   Am J Physiol Gastrointest Liver Physiol 276: G795-G799, 1999.
4. Determinants of nitric oxide protection and toxicity in liver.
   Jianrong Li and Timothy R. Billiar.
   Am J Physiol Gastrointest Liver Physiol 276: G1069-G1073, 1999.
5. Therapeutic potential of nitric oxide donors and inhibitors.
   Marcelo N. Muscará and John L. Wallace.
   Am J Physiol Gastrointest Liver Physiol 276: G1313-G1316, 1999.

Genetic Disorders of Membrane Transport

1. Glucose galactose malabsorption.
   Ernest M. Wright.
   Am J Physiol Gastrointest Liver Physiol 275: G879-G882, 1998.
2. Regulation of CFTR by small molecules including HCO^-₃.
   Beate Illek, Horst Fischer, and Terry E. Machen.
   Am J Physiol Gastrointest Liver Physiol 275: G1221-G1226, 1998.
3. Congenital chloride diarrhea.
   Juha Kere, Hannes Lohi, and Pia Höglund.
   Am J Physiol Gastrointest Liver Physiol 276: G7-G13, 1999.
4. Wilson's disease and Menkes disease.
   Mark Schaefer and Jonathan D. Gitlin.
   Am J Physiol Gastrointest Liver Physiol 276: G311-G314, 1999.
5. The epithelial sodium channel and its implication in human diseases.
   Edith Hummler and Jean-Daniel Horisberger.
   Am J Physiol Gastrointest Liver Physiol 276: G567-G571, 1999.

Mechanisms of Hepatic Toxicity

1. TNF-induced liver injury.
   Cynthia A. Bradham, Jörg Plümpe, Michael P. Manns, David A. Brenner, and Christian Trautwein.
   Am J Physiol Gastrointest Liver Physiol 275: G387-G392, 1998.
2. Alcoholic liver injury involves activation of Kupffer cells by endotoxin.
   R. G. Thurman.
   Am J Physiol Gastrointest Liver Physiol 275: G605-G611, 1998.
3. Intracellular signaling in response to toxic liver injury.
   Brett E. Jones and Mark J. Czaja.
   Am J Physiol Gastrointest Liver Physiol 275: G874-G878, 1998.
4. Pathogenetic mechanisms involved in hepatitis C virus-induced liver diseases.
   Johnson Yiu-Nam Lau.
   Am J Physiol Gastrointest Liver Physiol 275: G1217-G1220, 1998.
5. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis.
   John J. Lemasters.
   Am J Physiol Gastrointest Liver Physiol 276: G1-G6, 1999.

Neural Injury, Repair, and Adaptation in the GI Tract

1. New insights into neuronal injury: a cautionary tale.
   Karen E. Hall and John W. Wiley.
   Am J Physiol Gastrointest Liver Physiol 274: G978-G983, 1998.
2. The elusive action of capsaicin on the vagus nerve.
   Peter Holzer.
   Am J Physiol Gastrointest Liver Physiol 275: G8-G13, 1998.
3. Role of the RET signal transduction pathway in development of the mammalian enteric nervous system.
   V. Pachnis, P. Durbec, S. Taraviras, M. Grigoriou, and D. Natarajan.
   Am J Physiol Gastrointest Liver Physiol 275: G183-G186, 1998.
4. Pathophysiology of GI motility related to interstitial cells of Cajal.
   Jan D. Huizinga.
   Am J Physiol Gastrointest Liver Physiol 275: G381-G386, 1998.
5. Genes, lineages, and tissue interactions in the development of the enteric nervous system.
   Michael D. Gershon.
   Am J Physiol Gastrointest Liver Physiol 275: G869-G873, 1998.

G Protein-Coupled Receptors in Gastrointestinal Physiology

1. CCK receptors: an exemplary family.
   Stephen A. Wank.
   Am J Physiol Gastrointest Liver Physiol 274: G607-G613, 1998.
2. Regulation of neuropeptide receptors in enteric neurons.
   Karen McConalogue and Nigel W. Bunnett.
   Am J Physiol Gastrointest Liver Physiol 274: G792-G796, 1998.
3. Asymmetry in plasma membrane signal transduction: lessons from brush-border Na⁺/H⁺ exchangers.
   M. Donowitz, S. Khurana, C. M. Tse, and C. H. C. Yun.
   Am J Physiol Gastrointest Liver Physiol 274: G971-G977, 1998.
4. Neural regulation of gastrointestinal smooth muscle.
   Kenton M. Sanders.
   Am J Physiol Gastrointest Liver Physiol 275: G1-G7, 1998.
5. Gastrointestinal peptide signaling through tyrosine phosphorylation of focal adhesion proteins.
   Enrique Rozengurt.
   Am J Physiol Gastrointest Liver Physiol 275: G177-G182, 1998.

Current Concepts in Mucosal Immunity

1. Antigen presentation in the intestine: new rules and regulations.
   Lloyd Mayer.
   Am J Physiol Gastrointest Liver Physiol 274: G7-G9, 1998.
2. One size fits all: nonclassical MHC molecules fulfill multiple roles in epithelial cell function.
   Richard S. Blumberg.
   Am J Physiol Gastrointest Liver Physiol 274: G227-G231, 1998.
3. Ontogeny and function of γδ T cells in the intestine.
   Martin F. Kagnoff.
   Am J Physiol Gastrointest Liver Physiol 274: G455-G458, 1998.
4. How epithelial transport of IgA antibodies relates to host defense.
   Michael E. Lamm.
   Am J Physiol Gastrointest Liver Physiol 1998 274: G614-G617.
5. Role of M cells in transepithelial transport of antigens and pathogens to the mucosal immune system.
   Marian R. Neutra.
   Am J Physiol Gastrointest Liver Physiol 274: G785-G791, 1998.

Cell Adhesion and Migration

1. Neutrophil adhesive interactions with intestinal epithelium.
   Charles A. Parkos.
   Am J Physiol Gastrointest Liver Physiol 273: G763-G768, 1997.
2. Leukocyte-endothelial cell adhesion in the digestive system.
   D. Neil Granger.
   Am J Physiol Gastrointest Liver Physiol 273: G982-G986, 1997.
3. Leukocyte adhesion and transmigration in the liver vasculature.
   Hartmut Jaeschke and C. Wayne Smith
   Am J Physiol Gastrointest Liver Physiol 273: G1169-G1173, 1997.
4. Lymphocyte trafficking in the intestine and liver.
   M. Salmi, D. Adams, and S. Jalkanen.
   Am J Physiol Gastrointest Liver Physiol 274: G1-G6, 1998.

Epithelial Cell Growth and Differentiation

1. Intestinal growth factors.
   D. J. Drucker.
   Am J Physiol Gastrointest Liver Physiol 273: G3-G6, 1997.
2. Intestinal apoptosis.
   C. S. Potten.
   Am J Physiol Gastrointest Liver Physiol 273: G253-G257, 1997.
3. Promoting diversity in the intestine: conversations between the microflora, epithelium, and diffuse GALT.
   J. I. Gordon, L. V. Hooper, M. S. McNevin, M. Wong, and L. Bry.
   Am J Physiol Gastrointest Liver Physiol 273: G565-G570, 1997.
4. Controlled spatiotemporal expression of transgenes: new tools to study normal and pathological states.
   Sylvie Robine, Frédéric Jaisser, and Daniel Louvard.
   Am J Physiol Gastrointest Liver Physiol 273: G759-G762, 1997.
5. Transcriptional regulation, development, and neoplasia of the intestinal epithelium.
   Peter G. Traber.
   Am J Physiol Gastrointest Liver Physiol 273: G979-G981, 1997.