Gastrointestinal Aging

Over the lifetime, changes occur to many organ systems. Aging individuals seek medical care for gastrointestinal-related complaints more often than any other age group. The gastrointestinal tract undergoes a number of changes with aging: including alterations to microbiota, epithelial functions, mucosal immunity, secretory, absorptive and neural functions. Age-associated changes in gastrointestinal functions also affect metabolic states, food intake and disease processes. Consideration of aging-related physiological principles in the gastrointestinal tract could be a key for better health and longer life, and is of great interest for the readers of the American Journal of Physiology-Gastrointestinal and Liver Physiology. Deadline: 12/1/17.


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