General Titles

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Titles in this Series


Nathan Zuntz: His Life and Work in the Fields of High Altitude Physiology and Aviation Medicine

Gunga, Hans Christian
Originally Published by Academic Press 2009
2008, 272 p.
ISBN 978-1-4614-7575-0

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ABOUT THIS BOOK

  • Focuses on Zuntz's contribution to high altitude physiology and aviation medicine
  • Discusses high altitude physiology and aviation
  • Biography of German physiologist 1847-1920

This book focuses on the life and work of Nathan Zuntz (1847-1920), a German physiologist, who made significant contributions to high altitude physiology and aviation medicine.

TABLE OF CONTENTS

Biography • Scientific work • On the development of aeronautics and aeronautic medical research in Berlin from 1880 to 1918 • Conclusion


Exercise Physiology: People and Ideas

Tipton, Charles M (Ed.)
Originally Published by Elsevier 2001
2003, 528 p.
ISBN 978-1-4614-7543-9

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ABOUT THIS BOOK

  • This is the first history of exercise physiology written from a systems perspective
  • Significance of human exercise experiments is emphasized
  • Chapter authors are leaders in the field who have received many honors, including the Olympic prize in the sport sciences

This is the first history of exercise physiology written from a systems perspective. The significance of human exercise experiments is emphasized, and the range of coverage is very wide. Among the figures whose thinking or work are discussed are Galen, Avicenna, Descartes, Edward Smith, Seguin, Krogh, A.V. Hill, Henry Taylor, Zuntz, Ingle, Palladin, Galbo, and Bloor. Throughout the book controversies are acknowledged and differences of viewpoint presented. After an introductory chapter on early ideas about the physiology of exercise and the training of athletes, there are eleven in-depth accounts of the development of scientific thinking about the responses of key physiological systems to the conditions of acute and chronic exercise, as well as their coupling with integrative responses. They cover the neuromuscular, cardiovascular, respiratory, autonomic, oxygen transport, metabolic, renal, endocrine and temperature regulation systems, among others. The authors of these chapters are very well-qualified. Two have received the Olympic Prize in the sport sciences, seven the Honor Award for Research in sports medicine and exercise science, and five have given the Adolph Lecture in environmental and exercise physiology for the American Physiological Society. No other volume offers such a broad and authoritative set of historical perspectives on exercise physiology.

TABLE OF CONTENTS

Ancient and Early Influences • The Neuromuscular System • The Cardiovascular System • The Respiratory System • The Autonomic Nervous System • The Oxygen Transport System and Maximal Oxygen Uptake • The Metabolic Systems: Aerobic Metabolism and Substrate Utilization in Exercising Skeletal Muscle • The Metabolic Systems: Anaerobic Metabolism (Glycolytic and Phosphagen) • The Endocrine System: Metabolic Effects of the Pancreatic, Adrenal, Thyroidal, and Growth Hormones • The Temperature Regulatory System • The Renal System • The Gastrointestinal System


High Life: A History of High-Altitude Physiology and Medicine

West, John B
Originally Published by Oxford University Press 1988
1998, 493 p.
ISBN 978-1-4614-7573-6

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ABOUT THIS BOOK

  • Features a complete history of high-altitude physiology and medicine
  • Comprehensive reference text which should be of value to anyone interested in high altitude and hypoxia
  • Including 185 illustrations

The history of high-altitude physiology and medicine is such a rich and colorful topic that it is surprising no one has undertaken a comprehensive account before. From the early balloonists to various high-altitude expeditions, culminating in the great feat of climbing Mount Everest without supplementary oxygen, the basic biological challenge of hypoxia has underpinned the human experience at high altitude. Of key importance in several areas of medicine including pulmonology, critical care, anesthesiology and cardiology, this topic is also of general interest to other life sciences such as biology and ecology, because hypoxia is encountered by many organisms throughout the animal kingdom.

High Life covers the topic from its earliest beginnings with the Greeks to the last two or three years, and highlights many geographical locations, such as China, Japan, India and Russia. Including 185 illustrations, over 800 references, and three appendixes detailing the chronology of main events, databases of high-altitude publications, tables of high-altitude locations, a list of classical books on the topic and narratives of classical and modern high-altitude expeditions, this book is a comprehensive reference text which should be of value to anyone interested in high altitude and hypoxia.

TABLE OF CONTENTS

From Classical Greece to the End of the Seventeenth Century • Eighteenth Century to Paul Bert • Early High-Altitude Stations and Field Studies • Oxygen Transfer by Lung and Blood, and the Controversy on Oxygen Secretion • History of High-Altitude Diseases • Early Expeditions to Mt. Everest • Permanent Residents of High Altitude • World War II • First Ascents of Mt. Everest • Studies in the 1960s and 1970s • Studies at Extreme Altitude • Other Recent High-Altitude Studies


August and Marie Krogh: Lives in Science

Schmidt-Nielsen, Bodil
Originally Published by Oxford University Press 1995
1995, 336 p.
ISBN 978-1-4614-7530-9

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ABOUT THIS BOOK

  • Biography of August and Marie Krogh
  • Focuses on their contributions to the physiology community
  • Written by the proud daughter of August and Marie Krogh

August Krogh, the son of a brewer, studied zoology in Copenhagen and earned his doctoral degree under the physiologist Christian Bohr, the father of the world-renowned nuclear physicist Niels Bohr. Krogh's unusual ability to construct instruments and complex apparatuses and his intuitive understanding of physical principles made it possible for him to improve on Bohr's methods. His findings led him to challenge Christian Bohr's ideas about oxygen secretion, and when Bohr refused to accept his findings, Krogh unwillingly came into a painful conflict with his own mentor. Krogh's continued studies of how oxygen is supplied to the tissues led to his realization that the blood flow in the finest blood vessels, the capillaries, has to be regulated through a mechanism that opens and closes the capillaries according to the tissue's need for oxygen. This idea and his scientific proof were at the time so new and revolutionary that he was promptly (in 1920) awarded the Nobel Prize. His fame in Denmark and all over the world continued to grow until his death in 1949. His scientific discoveries extended from respiration, exercise physiology and capillary physiology into comparative osmoregulation, isotope studies, active transport of ions in plants and animals, and finally insect flight.

Another dramatic story of Krogh's life began when he introduced insulin production in Denmark in 1922. This move saved his own wife's life as well as numerous other lives and helped make Denmark's Novo-Nordisk the largest producer of insulin in the world today. Krogh's wife, Marie, became a physician and a renowned scientist in her own right. Throughout their harmonious marriage and partnership, Marie played an important role in her husband's life both scientifically and personally.

Written by the proud daughter of August and Marie Krogh, this biography is based on numerous letters, scientific papers, interviews, symposia, and other sources as well as the author's own knowledge of her parents. The intertwining of the scientific work and personal lives of these two remarkable people is beautifully illustrated in a well-rounded picture of their struggles and triumphs. It is a unique book, full of human warmth and scientific understanding.

TABLE OF CONTENTS

Introduction • Ancestry • Childhood in Grenaa • School Years in Aarhus • Becoming a Zoologist • Becoming a Physiologist • The Beginning of Zoophysiology • August and Marie • Marriage and the Seegen Prize • The Oxygen Secretion Controversy • The Zoophysiological Laboratory and the Beginning of Exercise Physiology • Capillaries and the Nobel Prize • The Insulin Story • The Happiest Years • Capillary Function and the Contractility Controversy • New Fields of Investigation • Exercise Physiology • The Introduction of Isotopes • Dark Clouds • Exile in Sweden • The Private Laboratory in Gentofte • Last Scientific Work • Epilogue


A History of Gastric Secretion and Digestion: Experimental Studies to 1975

Davenport, Horace W
Originally Published by Oxford University Press 1992
1992, 432 p.
ISBN 978-1-4614-7602-3

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ABOUT THIS BOOK

  • A comprehensive review of the early history of gastric physiology
  • Examines the history of experimental study in gastric secretion and digestion
  • Provides gastric physiologists and gastroenterologist with a solid understanding of the intellectual history of their field

This book examines the history of experimental study in gastric secretion and digestion. The author identifies the scientific questions that have occupied researchers and discusses the experiments that have led to their solutions. By isolating aspects of experimental study and tracing their evolution over the years, the book provides gastric physiologists and gastroenterologists with a solid understanding of the intellectual history of their field.

TABLE OF CONTENTS

Secretion of Hydrochloric Acid • Pepsins and Pepsinogens • Mucus and Cell Renewal • Reflex Control of Gastric Secretion • Histamine • Chemical Control of Gastric Secretion • The Gastric Mucosal Barrier • Gastric Blood Flow and Secretion • Gastric Digestion and Absorption


Physiology in the American Context, 1850-1940

Geisson, Gerald L. (Ed.)
Originally Published by Lippincott William and Wilkins 1987
1987, 406 p.
ISBN 978-1-4614-7528-6

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ABOUT THIS BOOK

  • A study of physiology in America
  • Discusses the development of American physiology in the cultural context of the period
  • Covers social and institutional history

A study of physiology in America, this places the development of American physiology in the cultural context of the period. Divided into three parts, the book covers social and institutional history; physiology in relation to other fields; and instruments, materials and techniques.

TABLE OF CONTENTS

Toward a History of American Physiology • American Physiologists in German Laboratories, 1865-1914 • Growth of American Physiology, 1850-1900 • Physiology of the Future: Institutional Styles at Columbia and Harvard • A. B. Macallum and Physiology at the University of Toronto • International Relations and Domestic Elites in American Physiology, 1900-1940 • Biological and Medical Societies and the Founding of the American Physiological Society • Physiology, Biology, and the Advent of Physiological Morphology • General Physiology and the Discipline of Physiology, 1890-1935 • Pathologists, Clinicians, and the Role of Pathophysiology • Industrial Fatigue and the Discipline of Physiology • Physiological Identity of American Sex Researchers Between the Two World Wars • Cardiac Physiology and Clinical Medicine? Two Case Studies • Instruments and an Independent Physiology: The Harvard Physiological Laboratory, 1871-1906 • Research Materials and Reproductive Science in the United States, 1910-1940 • Instruments, Techniques, and Social Units in American Neurophysiology, 1870-1950


History of the American Physiological Society: The First Century, 1887-1987

Brobeck, John R., Reynolds, Orr E., Appel, Toby A. (Eds.)
Originally Published by Oxford University Press 1987
1987, 542 p.
ISBN 978-1-4614-7576-7

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ABOUT THIS BOOK
  • Reviews actives of the APS during the first 100 years
  • Celebrating the centennial of the APS
  • Chapters include membership, publications, organization, and awards
Celebrating the centennial of the American Physiological Society, this new book reviews the activities during the Society's first hundred years. The first section covers materials from the Society's founding in 1887 and a review of each of the first 25 year periods of the Society's existence. The second section includes a chronological account of the Presidents and the Executive Secretary-Treasurers. Also included are chapters on membership, publications, meetings, financial affairs, educational activities, organization of the Society, neurophysiology, relations with IUPS, women in physiology, use and care of laboratory animals, awards and honors, and the centennial celebration.

TABLE OF CONTENTS

Physiology Flourishes in America • Founding • First Quarter Century 1887–1912 • Second Quarter Century 1913–1937 • Third Quarter Century 1938–1962 • Presidents, 1888–1962 • Presidents, 1963–1987 • Executive Secretary-Treasurers • Membership • Spring and Fall Scientific Meetings • Publications • Educational Programs • Finances • Women in Physiology • Use and Care of Laboratory Animals • FASEB and the APS • International Physiology • Neuroscience • Sectionalization • Porter Physiology Development Program • Perkins Memorial Fund • Awards and Honors • Centennial Celebration


Animal Stress

Moberg, Gary P (Ed.)
Originally Published by Lippincott William and Wilkins 1985
1985, 332 p.
ISBN 978-1-4614-7544-6

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ABOUT THIS BOOK

  • Based on a 1985 symposium on animal stress
  • Provides up-to-date discussion of the problems and methods of studying animal stress today
  • Invaluable reference for those exploring complex responses in animals

Based on a recent symposium that brought together experts in behavior, nutrition, physiology, immunology, and human and animal medicine, this volume presents an up-to-date discussion of the problems and methods of studying animal stress today. Section one reviews the evolutionary and ontogenetic determinants of animal suffering and the assessment of well-being. The second section examines biological responses to stress and methods of monitoring stress in animals. Section three shows how stress can threaten animal health, disrupt normal reproduction, and influence growth and metabolism. The final section relates the importance of animal stress to developing guidelines on the use of animals in scientific research. This is an invaluable reference for exploring these complex responses.

TABLE OF CONTENTS

What Constitutes Animal Well-Being? • Evolutionary and Ontogenetic Determinants of Animal Suffering and Well-Being • Biological Response to Stress: Key to Assessment of Animal Well-Being? • A Definition of Stress? • Behavioral Responses to Stress in Farm Animals • Stress in Domestic Animals: A Psychoneuroendocrine Approach • Spontaneous Oscillations in Heart Rate: Potential Index of Stress • Assessment of Pain in Animals • Implantable Biotelemetry and Social Separation in Monkeys • Specific Effects of Stress on Disease Processes • Stress-Induced Immunomodulation: What Is It, If It Is? • Immunological Consequences of Changing Environmental Stimuli • Cortisol as Mediator of Stress-Associated Immunosuppression in Cattle • Influence of Stress on Reproduction: Measure of Well-being • Influence of Stress on Protein Metabolism • Regulations and Guidelines for Animal Care: Problems and Future Concerns • Definition of Laboratory Animal Environmental Conditions


Voltage and Patch Clamping with Microelectrodes

Smith, Thomas G; Lecar, Harold; Redman, Steven J (Eds.)
Originally Published by Lippincott William and Wilkins 1985
1985, 312 p.
ISBN 978-1-4614-7601-6

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ABOUT THIS BOOK

  • Edited and authored by international experts on voltage and patch clamping
  • Designed to help anyone undertaking experiments requiring the use of voltage and patch clamping techniques
  • Deepens knowledge on voltage and patch clamping

Edited and authored by international experts on voltage and patch clamping, this volume is designed to help anyone undertaking experiments requiring the use of these techniques. The only book of its kind to bring together this wealth of information on theory as well as practical techniques, this is a volume that no one involved in voltage and patch clamping can afford to be without.

TABLE OF CONTENTS

Introduction • Useful Circuits for Voltage Clamping With Microelectrodes • Microelectrode Shielding • Conventional Voltage Clamping With Two Intracellular Microelectrodes • Optimal Voltage Clamping With Single Microelectrode • High-Resolution Patch-Clamp Techniques. Voltage Clamp and Internal Perfusion With Suction-Pipette Method • Microelectrode Voltage Clamp: The Cardiac Purkinje Fiber • Space-Clamp Problems When Voltage Clamping Branched Neurons With Intracellular Microelectrodes • Comparison of Voltage Clamps With Microelectrode and Sucrose-Gap Techniques • Voltage Clamping Small Cells


Animal Pain: Perception and Alleviation

Kitchell, Ralph L; Erickson, Howard H (Eds.)
Originally Published by Lippincott William and Wilkins 1983
1983, 250 p.
ISBN 978-1-4614-7562-0

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ABOUT THIS BOOK

  • Intended as a source of basic information about the perception and alleviation of pain in animals
  • Useful for scientific investigators working in this area
  • Reflects the results of a 1982 landmark symposium on animal pain sponsored in part by the APS

This book is intended as a source of basic information about the perception and alleviation of pain in animals. It is especially useful for scientific investigators working in this area; for veterinarians interested in the health and welfare of animals, the assessment of pain during surgery, and the alleviation of pain; and for individuals involved in federal, state, and local regulation of the use of animals in research and education. Reflecting the results of a 1982 landmark symposium on animal pain sponsored in part by the American Physiological Society, this outstanding reference covers such topics as peripheral, supraspinal, segmental, and neurophysiological mechanisms involved in pain; spinal cord pathways and control systems; stimulation analgesia and endorphins; behavioral mechanisms for assessing pain; and the phylogenetic evaluation of pain expression in animals.

TABLE OF CONTENTS

Peripheral Mechanisms Involved in Pain • Neurophysiological Mechanisms of Nociception • Ascending Pathways Transmitting Nociceptive Information in Animals • Supraspinal Pain Mechanisms in the Cat • Descending Control of Spinal Nociceptive Transmission • Stimulation-Produced Analgesia • Human and Nonhuman Primate Reactions to Painful Electrocutaneous Stimuli and to Morphine • Concepts of General Anesthesia and Assessment of Adequacy of Anesthesia for Animal Surgery • Perspectives on Phylogenetic Evolution of Pain Expression • Species Differences in Drug Disposition as Factors in Alleviation of Pain • Evaluation of Analgesic Drugs in Horses • Control of Pain in Dogs and Cats


Circulation of the Blood: Men and Ideas

Fishman, Alfred P.; Richards, Dickinson W. (Eds.)
Originally Published by Lippincott William and Wilkins 1982
1983, 879 p.
ISBN 978-1-4614-7546-0

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ABOUT THIS BOOK

  • Comprehensive coverage of circulation of blood
  • Explores personal elements involved in scientific discovery
  • Renowned authors write chapters on their extensive experience in the field of blood circulation

Capturing the real spirit of creativity in physiology, this book explores the personal elements involved in scientific discovery. Circulation of the Blood is the story of the people and achievements that have changed the way we've come to view the human body. The authors, renowned for their extensive experience in the field, examine the heritage of creative genius involved in physiology and trace the historical development of ideas relating to various aspects of circulation of the blood. Their comprehensive coverage goes from the early discoveries of the Greeks and Romans up to modern times.

TABLE OF CONTENTS

Air and Blood • The Output of the Heart • Heart Muscle • Coronary Circulation and Cardiac Metabolism • Electrocardiography • The Capillary Circulation • Vasomotor Control and the Regulation of Blood Pressure • Systemic Arterial Hypertension • Renal Physiology • The Splanchnic Circulation • The Cerebral Circulation • Physiological Changes in the Circulation after Birth


History of the American Physiological Society: The Third Quarter Century, 1937-1962

Fenn, Wallace O.
Originally Published by American Physiological Society 1963
1962, 182 p.
ISBN 978-1-4614-7603-0

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ABOUT THIS BOOK

  • History of the APS
  • Focuses on the third quarter century 1037-1962
  • Written by prominent researcher Dr. Wallace O. Fenn

This book focuses on the History of the American Physiological Society. Specifically it focuses on the third quarter century period of it's history: 1937-1962. Authored by prominent researcher Dr. Wallace O. Fenn of University of Rochester, NY, USA.

TABLE OF CONTENTS

Introduction • Chronological Account of the Presidents of the Society • Membership • Publications • Fall Meetings • Ancillary Groups • Organization of the Society • Some Changes in the Character of the Society • Relations with Other Organizations • Use and Care of Laboratory Animals • Porter Fellowship • Early Reminiscences • Educational Activities in the Society • Summary of Financial Growth of the Society


Mirror to Physiology: A self-survey of physiological science

Gerard, Ralph W
Originally Published by American Physiological Society 1958
1958, 372 p.
ISBN 978-1-4614-7538-5

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ABOUT THIS BOOK

  • Survey report of mirror to Physiology
  • Published by the APS
  • Written by Dr. Ralph W. Gerard

TABLE OF CONTENTS

The Survey in Brief • Origin and Objectives of the Survey • The Survey in Operation • Defining Physiology and Physiologists • Activities, Employment and Income of Physiologists • Occupational Motivations, Satisfactions, and Mobility • Research Activities and Programs • Research Facilities and Support • Professional Communication: Publications and Societies • Professional Training and Recruitment • The Public and Physiology: Communication and Education • Interpretations and Recommendations


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