Arnold M. Katz
July 30-1932 - January 25, 2016
Dr. Katz was born in Chicago on July 30, 1932. His mother, a graduate of the Cleveland Conservatory of Music, was a piano teacher. Louis N. Katz, his father, was an internationally renowned cardiologist and basic science investigator who received a Lasker award, and was President of the American Physiological Society and American Heart Association.
Dr. Arnold Katz received his early education at the University of Chicago Laboratory Schools, and graduated from the University of Chicago College in 1952 earning a B.A. with Honors in the Natural Sciences. While a college student he studied yeast metabolism during the summer of 1951 and spent the summer of 1952 at the Marine Biological Laboratory in Woods Hole, MA where he participated in a study of the physicochemical properties of muscle. While a medical student at Harvard he spent the summers of 1953 and 1954 with his father in Chicago studying coronary flow, left ventricular volume curves and the energetics of the heart.
After receiving his M.D. cum laude from Harvard in 1956, Dr. Katz did a medical internship at the Massachusetts General Hospital. As an intern he published the only known autocthonous case of Echinococcus disease in Massachusetts along with a review of 79 cases seen at the Massachusetts General and 556 cases reported from the United States; this paper is still cited in major internal medicine texts. He then spent two years in the Laboratory of Dr. C. B. Anfinsen Jr. at the National Institutes of Health in Bethesda MD, where he worked on protein chemistry; a paper on peptide separation and analysis, published in 1959 with Dr. Anfinsen, was identified by Current Contents as among the 200 most cited papers.
In 1959 he returned to the Massachusetts General as a medical assistant resident after which he was awarded a Moseley Travelling Fellowship from Harvard to spend a clinical year as at the National Heart Hospital in London with Dr. Paul Wood. While in London he published a study of fibrinolysis in patients with coronary disease, and with his wife Phyllis, a classicist, reviewed possible descriptions of heart disease in the works of Hippocrates. He returned to the United States in 1961 to begin work on muscle biochemistry at the University of California at Los Angeles as an Advanced Research Fellow and subsequently Established Investigator of the American Heart Association. During his 3 years at UCLA he published a series of papers comparing the contractile proteins of heart and skeletal muscle, and was among the first to define the role of tropomyosin, troponin and calcium in regulating the interactions between the contractile proteins of skeletal and cardiac muscle.
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