My Career in Science - Gabor Kaley -- TOC
Living History Project � Gabor Kaley
00:01:58 Dr.
Kaley, although a detailed biographical profile of you career as a physiologist
will be published in a subsequent issue of Advances in Physiology Education,
could you please provide our viewers with some background information of your
education in Hungry before you came to the United Sates and enrolled in Columbia
University?
00:06:40
What were the factors, Dr. Kaley, that led you then to seek your Masters degree
and eventually your Ph.D. degree in Experimental Pathology at New York
University?
00:08:56 How
was it that at New York University you were able to find Dr. Benjamin W.
Zweifach who was at that time a nationally and international renowned researcher
in the field of Microcirulation. Was Dr. Zweifach,
your mentor and how important was he in defining your area of interest?
00:14:06 It
sounds like your situation in New York University was indeed exciting I also
noticed that some of your early work related to the Renin Angiotensin system.
How did that come about?
00:19:26 It
sounds like this was one of the most seminal findings with regard to the rennin
angiotensin system at that time in terms of the evolutionary adherence of it.
Later on, it seems that in the 60�s and 70�s you moved on to investigate the
role of ����������������� prostaglandins and inflammation. In fact, you�ve been
credited with the seminal influence for study in this particular field. Who and
what influenced you to become interested in prostaglandins and what were the
important findings related to these biologically active compounds?
00:20:47 Is
this what brought you then to New York Medical College at that time?
00:27:57 It
seems that in your history that you did study prostaglandins and you continued
to study them but you shifted your role more from inflammation rather into the
role of prostaglandins with regards to the regulation of blood flow and blood
pressure. What were some of your key findings in this particular area?
00:33:18 You
did spend a lot of time studying the prostaglandins so I guess at this junction
we would ask you what important questions remain scientifically in terms of the
role of prostaglandins from a cardiovascular standpoint and where do you see
future research potentially going?
00:36:18
While your research was progressing in the area of prostaglandins, along came
another molecule, nitric oxide. How was it that you entered this particular
field and what were some of the key findings from your laboratory?
00:46:03 It
was interesting to see that you took this paradigm and extended it into looking
at the role of either prostaglandins or nitric oxide in contributing to vascular
responses during exercise and ageing and hypertension as well as under the
influence of a variety of sex hormones. Could you summarize for us briefly what
the key findings were in some of those areas?
00:56:19
Earlier on in the interview process you mentioned the name of Dr. Benjamin
Zweifach as being very influential in setting you on your career path. Have
there been any individuals, either prominent researchers or Physiologists that
have determined some of the directions you have taken?
01:09:15 Dr.
Kaley has had an illustrious career as both a teacher and researcher. He has
trained well over a hundred some odd masters to go on in a variety of careers
whether they be within a medical University setting or University or within the
Pharmaceutical industry. He�s also be a participant in the training of close to
200 individuals who have received their Ph.D. under his sponsorship. So at this
junction Dr. Kaley, I�d like to ask you: what do you think is the secret to
being a successful sponsor?
01:12:53 For
our viewers you should also know that Dr. Kaley just recently in September of
2007, stepped down as Chairman of the Department of Physiology here at New York
Medical College and one of his ex-students Dr. Tomas Hensey has now been
nominated, elected, and fully installed as the new chairman of the Department of
Physiology here. Dr. Kaley, as the American Physiological Society enters the 21st
Century, what advice would you give to its Council and Long Range Planning
Committee?