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Samuel L. Leonard
November 26, 1905 - November 11, 2007

As posted on United Press International (http://www.upi.com/).

Man who laid in vitro groundwork dies

Published: Nov. 23, 2007 at 2:34 PM

ITHACA, N.Y., Nov. 23 (UPI) -- Samuel Leonard, whose study of reproductive hormones in animals helped lay the basis for in vitro fertilization in women, died in Ithaca, N.Y. He was 101.

When endocrinology was in its infancy in the 1930s, Leonard, as a University of Wisconsin doctoral student working with his thesis adviser and another researcher, determined the pituitary gland produces two hormones with distinct effects on the sexual organs, The New York Times reported.

When Leonard and his collaborators published their results in the American Journal of Physiology, they "created a storm that opened a series of investigations and fruitful research," Robert H. Foote, a professor emeritus of animal physiology at Cornell University, where Leonard taught for many years, told the Times.

In his research, Leonard worked mostly with laboratory rats and became adept in brain surgery, a necessity for reaching and removing the pituitary.

Colleague Ari Van Tienhoven, a professor emeritus of animal physiology at Cornell, commented on Leonard's skilled operations, saying he could "perform surgery, smoke a cigar and remove a rat's pituitary in a blue haze, all in about 10 minutes."

Leonard, who died Nov. 11, is survived by a daughter, four grandchildren and one great-grandchild.