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Mediators of Liver Inflammation
APS Gastrointetinal & Liver Section
Alex B. Lentsch
P. Kubes, M. Clemens, T. Billiar and H. Jaeschke
This symposium will broadly address the topic of liver dysfunction
induced by a variety of causes including sepsis, trauma/hemorrhage, and
ischemia/reperfusion. The session will provide the audience with a
comprehensive discussion of important mediators of the hepatic inflammatory
response, ranging from cell surface-expressed adhesion molecules to secreted
proteins to oxygen metabolites, and their roles in the induction and
propagation of liver inflammation and injury. By its nature, the symposium
will also provide a discussion of the clinical relevance of these topics and
how therapeutic targets are identified.
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