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New Genomic Technologies for Systems Biology
APS Physiological Genomics Group
Anne Kwitek
A. Pack, M. Michalkiewicz, M. Gould and B. Davidson
The substantial success of the genomic era has provided the
infrastructure to identify all genes in human and other model organisms.
These data, made publicly available to all, is leading the way to the
critical question of what is gene function and how does it relate to the
pathology of disease. Part of the complication of understanding gene
function, particularly in relation to complex disease, is being able to
study its effect in whole animal systems. This symposium focuses on how new
genomic technologies are being applied within whole animal physiology to
determine the functional role of genes in disease. Approaches to be
addressed are microarray, BAC transgenics a novel method of gene knockout,
and in vivo siRNA studies.
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