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A Bioinformatics How-to for the Wet-Lab Physiologist
APS Physiological Genomics Group
Howard Jacob
C. Kendziorski, E. Green, A. Kwitek and T. Paterson
Understanding the mechanisms of complex systems biology
is greatly facilitated by merging computational approaches with good systems
biology. Bioinformatic tools and databases for genomic information offer
comprehensive information that can facilitate the better understanding of
disease mechanisms; however, knowing where to go to find publicly available
information as well as how to best utilize the data to better direct
physiological research can be daunting. This symposium serves to give
instruction on the applications of bioinformatics tools and databases to
address physiological genomics. Subjects to be discussed include:
integrating information from the public databases, analyzing large scale
microarray data, using comparative genomics for understanding human
pathophysiology, and using in silico methods to predict clinical
outcomes of treatment.
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