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9560 rockville pike, bethesda, MD 20814-3991
 

 


Live Cell Imaging of the Microcirculation: Experimental Approaches
Sponsored by
The Microcirculatory Society
 

Saturday, April 18 — 2:00 PM-4:30 PM
Ernest N. Morial Convention Center, Room 255-257
 
Chaired:

Steven S. Segal, Univ. of Missouri-Columbia

This afternoon’s workshop follows from the morning President’s Symposium.  Each speaker from the morning session will give a 25-30 minute presentation in which they discuss the underlying experimental techniques and procedures that were used to acquire the images and functional measurements presented earlier. Dr. Balaban will explain methods for imaging metabolic signals in light of microvascular perfusion in response to contractile activity of striated muscle. Dr. Iadecola will present methods for evaluating local regulation of cerebral blood flow in response to regional neural activity. Dr. Mcgavern will explain how fatal immune-mediated vascular injury is observed in the virally-infected CNS. Dr. Dickinson will present methods for intravital monitoring of hemodynamic forces underlying vascular development. Each presentation will be followed by 5-10 minutes of discussion. Dr. Segal will give a brief introduction and mediate the ensuing questions and discussion. 

2:00 PM Introduction.
Steven S. Segal, Univ. of Missouri-Columbia
2:05 PM Noninvasive imaging of mitochondrial and microvascular function in striated muscle.
Robert S. Balaban, NIH, NHLBI
2:40 PM Imaging the signaling events that couple cerebral blood flow with neural activity.
Constantino Iadecola, Cornell Univ.
3:15 PM Visualizing immune-mediated vascular injury in the virally infected CNS.
Dorian B. Mcgavern, NIH, NINDS
3:50 PM Imaging changes in vascular cytoarchitecture in response to blood flow in embryos.
Mary Dickinson, Baylor Col. of Med.
4:25 PM Concluding questions and comments.