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Myriad Mechanisms Underlying the Pathophysiology of
Diabetes
Sponsored by APS Cardiovascular Section
Metabolism and Energy Track
Wednesday, April 9 — 8:00 AM-10:00 AM
San Diego Convention Center — Room 23
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Chaired: |
Cuihua
Zhang, Texas A&M Univ.
Ann
Marie Schmidt, Columbia Univ. |
This Cardiovascular Seminar is to summarize the
latest breakthroughs and concepts about the pathophysiological
manifestations of diabetes on the heart and vasculature. The specific
orientation of this session will focus on metabolomics in diabetes, that
is, the systematic study of the unique chemical fingerprints that
specific cellular processes leave behind, from the perspectives of the
different speakers: the feed forward response of AGE/RAGE and cytokines
on oxidative stress, the details of AGE/RAGE signaling in the production
of ROS, the impact and causes of mitochondrial oxidative stress in
diabetes, and the role that alterred stem cell biology plays in diabetic
cardiomyopathy. The subjects should attract a wide audience of
individuals involved in cardiac and vascular biology, and even be of
interest to individuals working in ROS signaling and studying
renovascular complications in diabetes.
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8:00 AM |
The basis
for vascular inflammation in diabetes.
Cuihua Zhang, Texas A&M Univ.
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8:25 AM |
Discussion |
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8:30 AM |
AGE/RAGE
interactions in diabetes.
Ann
Marie Schmidt, Columbia Univ.
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8:55 AM |
Discussion |
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9:00 AM |
Is
Diabetic Vasculopathy Related to Altered Stem Cell Function?
Piero Anversa,
New York Med. Col.
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9:25 AM |
Discussion |
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9:30 AM |
Biochemistry and molecular cell biology of diabetic complications.
Michael Brownlee,
Albert Einstein Col. of Med.
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9:55 AM |
Discussion |
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