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9560 rockville pike, bethesda, MD 20814-3991
 

 


Myriad Mechanisms Underlying the Pathophysiology of Diabetes
Sponsored by APS Cardiovascular Section
Metabolism and Energy Track

Wednesday, April 9 — 8:00 AM-10:00 AM
San Diego Convention Center — Room 23
 

Chaired:

Cuihua Zhang, Texas A&M Univ.

Ann Marie Schmidt, Columbia Univ.

This Cardiovascular Seminar is to summarize the latest breakthroughs and concepts about the pathophysiological manifestations of diabetes on the heart and vasculature.  The specific orientation of this session will focus on metabolomics in diabetes, that is, the systematic study of the unique chemical fingerprints that specific cellular processes leave behind, from the perspectives of the different speakers:  the feed forward response of AGE/RAGE and cytokines on oxidative stress, the details of AGE/RAGE signaling in the production of ROS, the impact and causes of mitochondrial oxidative stress in diabetes, and the role that alterred stem cell biology plays in diabetic cardiomyopathy.  The subjects should attract a wide audience of individuals involved in cardiac and vascular biology, and even be of interest to individuals working in ROS signaling and studying renovascular complications in diabetes.

8:00 AM

The basis for vascular inflammation in diabetes.

Cuihua Zhang, Texas A&M Univ.
 

8:25 AM

Discussion

8:30 AM

AGE/RAGE interactions in diabetes.

Ann Marie Schmidt, Columbia Univ.
 

8:55 AM

Discussion

9:00 AM

Is Diabetic Vasculopathy Related to Altered Stem Cell Function?

Piero Anversa, New York Med. Col.
 

9:25 AM

Discussion

9:30 AM

Biochemistry and molecular cell biology of diabetic complications.

Michael Brownlee, Albert Einstein Col. of Med.
 

9:55 AM

Discussion