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Caveolae and Caveolins in Cardiovascular Physiology and Disease
Sponsored by APS Cardiovascular Section
Cell Physiology Track

This session is designed to provide an update for attendees on the substantial number of new developments related to the physiological and pathophysiological role of caveolae in the cardiovascular system. Recent data indicate that these plasma membrane microdomains are key sites that organize and concentrate multiple lipids and proteins involved in signaling and functional activities of cardiovascular cells, including endothelial cells, cardiac and vascular smooth muscle myocytes and cardiac fibroblasts. There has not been an APS Symposium on caveolae at EB for several years and none have emphasized the cardiovascular system. Such a Symposium will likely attract considerable interest (>400 people attended a more general Symposium on caveolae at the EB meeting several years ago) and will appeal to a wide range of physiologists, including not only those with primary interest in cardiovascular physiology but also investigators in the areas of  pulmonary, renal/electrolyte, GI, endocrine/metabolism and cell physiology. The session will also likely appeal to those in other EB societies, including ASPET, ASBMB, Experimental Pathology and Nutrition Societies.