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9560 rockville pike, bethesda, MD 20814-3991
 

 


Molecular Regulation of Renal Epithelial Transport Proteins in the Nephron: Lessons from Ontogeny and Disease
Sponsored by APS Renal Section and American Society for Nephrology
Transporters Track

Monday, April 30 — 10:30 AM-12:30 PM
Washington, DC Convention Center — Room 146C
 
Chaired:

Young Hee Kim, Emory Univ. Sch. of Med.
Lisa M. Satlin
, Mount Sinai Med. Ctr.

A thorough understanding of the ontogeny of renal ion and solute transport is required to best understand the contribution of the differentiating kidney to growth and homeostasis as well as the role of dysregulated transport   in the genesis of disease. Elucidation of the molecular basis for a number of single gene disorders associated with defects in tubular transport has provided important insight into the developmental pathways involved in establishing normal transepithelial transport and disease pathogenesis. This symposium will feature presentations that highlight recent advances in our understanding of the developmental regulation of epithelial transport and how these pathways contribute to the response of fully differentiated kidney to disease.    

10:30 AM

Regulation of renal collecting duct development by the p53 gene family.
Samir El-Dahr
, Tulane Univ. Hlth. Sci. Ctr.
 

11:00 AM

The role of hensin in the differentiation of intercalated cells and the response to metabolic acidosis.
George J Schwartz
, Univ. of Rochester Med. Ctr.
 

11:30 AM

Mechanisms of renal K secretion: lessons from ontogeny and disease.
Lisa M Satlin
, Mount Sinai Med. Ctr.
 

12:00 PM

Ontogeny of NaCl and water transporters in the collecting duct.
Young Hee Kim
, Emory Univ. Sch. of Med.