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Suspended Animation – Fact or Fiction?
Sponsored by APS Environmental & Exercise Physiology Section

Small rodents have the unique capability to enter suspended-like states of animation (i.e., regulated hypothermia) as a method of surviving severe environmental insults (e.g., heat, cold, hypoxia) and ischemia/reperfusion injury.  It has been hypothesized that the regulated induction of these suspended animation-like states may have clinical benefit in the treatment of injurious conditions that induce brain ischemia.  New insights into the signaling mechanisms and protective effects of suspended animation-like states are emerging.  This symposium will discuss the benefits of animation-like states in the mitigation of injury to different environmental stimuli and discuss recent findings with respect to novel chemical mediators that may be used to induce these protective conditions in the clinical arena.