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PPARg : A Novel Molecular Target in Lung Disease
Sponsored by
The American Federation for Medical Research
Translational Physiology
Track
Sunday, April 29 — 10:30 AM-12:30 PM
Washington, DC Convention Center — Room 146B
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| Chaired: |
Mike Hart, Emory Univ. and Atlanta VA Med. Ctr. |
Peroxisome proliferator-activated receptors (PPARs)
are members of the nuclear hormone receptor superfamily of ligand-activated
transcription factors. Emerging evidence indicates that
PPAR gamma (PPARg) regulates gene expression and function within
several cellular compartments of the lung. This symposium will
emphasize the therapeutic implications of these findings for seemingly
diverse types of lung disease and clarify current understanding of the
basic molecular and biochemical mechanisms by which PPARg participates
in lung cell biology.
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10:30 AM |
PPARg in the pathogenesis of lung cancer: implications for therapy.
Avery August, Penn State Univ.
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11:00 AM |
The immunomodulatory role of PPARg in alveolar macrophages.
Raju Reddy, Univ. of Michigan
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11:30 AM |
The anti-fibrogenic potential of PPARg ligands in pulmonary
fibrosis.
Patricia Sime, Univ. of Rochester
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12:00 PM |
The role of PPARg
in pulmonary vascular disease.
Mike Hart, Emory Univ. and Atlanta VA Med. Ctr.
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