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9560 rockville pike, bethesda, MD 20814-3991
 

 


PPARg : A Novel Molecular Target in Lung Disease
Sponsored by The American Federation for Medical Research
Translational Physiology Track

Sunday, April 29 — 10:30 AM-12:30 PM
Washington, DC Convention Center — Room 146B
 
Chaired:

Mike Hart, Emory Univ. and Atlanta VA Med. Ctr.

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors.  Emerging evidence indicates that PPAR gamma (PPARg) regulates gene expression and function within several cellular compartments of the lung.  This symposium will emphasize the therapeutic implications of these findings for seemingly diverse types of lung disease and clarify current understanding of the basic molecular and biochemical mechanisms by which PPARg participates in lung cell biology.

10:30 AM

PPARg in the pathogenesis of lung cancer: implications for therapy.
Avery August
, Penn State Univ.

 

11:00 AM

The immunomodulatory role of PPARg in alveolar macrophages.
Raju Reddy, Univ. of Michigan

 

11:30 AM

The anti-fibrogenic potential of PPARg ligands in pulmonary fibrosis.
Patricia Sime, Univ. of Rochester
 

12:00 PM

The role of PPARg in pulmonary vascular disease.
Mike Hart
, Emory Univ. and Atlanta VA Med. Ctr.