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9560 rockville pike, bethesda, MD 20814-3991
 

 


Tubule Perfusion: 40 Years Old And Still Going Strong
Sponsored by the APS Renal Section

Tues. April 4—10:30 AM-12:30 PM
 
Chaired:

Maurice Burg, NHLBI, NIH
Jeff M. Sands
, Emory Univ.

2006 will be the 40th anniversary of the first tubule perfusion study.  Tubule perfusion resulted in many pioneering studies of renal tubular transport. It remains the gold standard of transport physiology.  This symposium marking this anniversary will feature cutting edge research involving tubule perfusion. Dr. Ortiz will present new studies of protein trafficking in isolated thick ascending limbs, including studies of transgenic mice.  Dr. Pech will present studies about the role of Pendrin in acid-base and chloride transport, including studies from Pendrin knock-out mice. Dr. Chou will present studies of the signaling pathways that regulate water transport in the collecting duct and studies from aquaporin knock-out mice. Dr. Wang will present studies of the mechanism of glomerulotubular balance that derive from studies of NHE3, AT1a and iNOS knockout mice.

10:30 AM

Introduction.
Maurice Burg
, NHLBI, NIH
 

10:35 AM

Studying protein trafficking in isolated thick ascending limbs
Pablo Ortiz
, Henry Ford Hosp.
 

11:05 AM

Role of pendrin in sodium chloride and acid-base transport.
Vladimir Pech
, Emory Univ.
 

11:35 AM

Vasopressin regulation of water transport in the collecting duct.
Chung-Lin
Chou
, NHLBI, NIH
 

12:05 PM

Flow-dependent sodium and bicarbonate transport in proximal tubules.
Tong Wang
, Yale Univ.