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Experimental Design



Knowing how to effectively design your experiments will not only save you time and effort, but it will allow you to be better able to actually answer the question you want to ask.

The APS and the Association of Chairs of Departments of Physiology recommend that trainees understand the importance of and work to develop the following problem experimental design skills:

a. Knowledge of the scientific method to organize and test ideas and hypotheses
b. Ability to recognize meaningful problems and questions for research
c. Ability to define the problem precisely
d. Knowledge of different research methodologies
e. Ability to select appropriate instruments to acquire data
f. Skill in designing experimental protocols, including appropriate use and number of experimental subjects
g. Understanding of the principles and procedures for institutional approval for use of animal/human subjects
h. Skill in evaluating experimental evidence
i. Ability to draw conclusions from data (data analysis)
(from the APS/ACDP List of Professional Skills for Physiologists and Trainees)

Here are a variety of web sites with information that you might find useful.*

Index:
Scientific Method
Defining the Question
Data Acquisition
Experimental Protocols
Evaluating Data
Drawing Conclusions


Scientific Method

APPENDIX E: Introduction to the Scientific Method
Frank Wolfs, University of Rochester

Research Methods Tutorials
William M.K. Trochim, Cornell University

The Scientific Method
J. Stein Carter, University of Cincinnati

The Whole Art of Deduction: Research Skills for New Scientists
Rodger Marion, The University of Texas Medical Branch

This Is The Scientific Method
Norman W. Edmund

Back to Index

Defining the Question

Defining a Research Problem
Faculty of Health Sciences, University of Sydney

Developing a Research Question
Empire State College, State University of New York

Defining Your Research Question
Geoff Soutar, ANZMAC Doctoral Colloquium, Queensland University of Technology, Australia

Formulating a Research Question
The Research Assistant, Danya International, Inc.

The Research Problem
Mike Kroelinger, Arizona State University

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Data Acquisition

Choosing a Methodology: Fitness for Purpose
hydi Educational New Media Centre, Massey University

Research Methodologies
The Centre for Teaching and Learning, University College Dublin

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Experimental Protocols

Experimentation
Department of Statistics, Yale University

Procedures in Sampling
William M.K. Trochim, Cornell University

Seven Resources for Young Scientists
Desmond Wong, ScienceCareers.org, AAAS

See also Use of Human/Animal Subjects

Back to Index

Evaluating Data

Chapter 3. Experimental Errors and Error Analysis
from Mathematica. Experimental Data Analyst
Wolfram Research, Inc.

Experimental Errors and Data Analysis
J.C. de Paula, Haverford College

Laboratory 0: Error Analysis
from Virtual Labs, Real Data
Cornell University

Measurement Errors
Appendix A: Handling Measurements
from Doing Science: An Introduction to Physical Science
Susan Wyckoff, Arizona State University

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Drawing Conclusions

Drawing Conclusions
Rodger Marion, The University of Texas Medical Branch

Pitfalls of Data Analysis
Clay Helberg, University of Wisconsin Schools of Nursing and Medicine

Quantitative Research Methods
Electronic Resources for Research Methods, InformationR.net

The Prism Guide to Interpreting Statistical Results
GraphPad.com

Using Statistics to Compare Groups
B. Baldwin, Southeastern Louisiana University

Back to Index

*APS does not endorse or assume responsibility for the information posted on these web sites.


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