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Who is David Pollock? From University to Drug Company and Back Again
David stayed in his hometown and went to college at the University of Evansville. He received a scholarship to continue as an athletic trainer for the college football, basketball, and baseball teams. His first two years in college as a biology major were rather uneventful, as he took the usual array of introductory classes. However, it was in his junior year when he took an advanced human physiology class that he experienced a “revelation.” With the help of a truly inspired teacher, Dr. Eugene Schroeder, David discovered that physiology was the subject that really got him excited. This experience made him want to learn more. He knew that in order to understand more about how the body works, he would have to continue his studies in graduate school. However, he first had to take time to get married to another biology major, Jennifer Pollock. David enrolled in the Ph.D. program at the University of Cincinnati and graduated with a degree in physiology in 1983. He then went to the University of North Carolina at Chapel Hill and worked as a post-doctoral fellow in the Department of Physiology. Although when he started graduate school he thought he would end up teaching college, Dr. Pollock decided that a career as an independent researcher was what he truly wanted. Using Physiology to Discover New DrugsDr. Pollock’s first job opportunity came in 1988 when he went to work at a research institute that was just being established by several faculty in the physiology department at Harvard Medical School in Boston. The institute struggled financially, and so when a job offer came along to work in the Drug Discovery Division at Abbott Laboratories a year and a half later, he took it. He got the job through a friend he had met while attending a meeting of the American Physiological Society. Working in Drug Discovery was quite exciting, and Dr. Pollock was able to apply his abilities as a physiologist to help develop several potential new drugs, including endothelin antagonists that should soon be approved for treatment of heart failure and prostate cancer.
Back to School
David spends most of his free time with his three children, Luke, Sam, and Michaela. They keep him busy with baseball, soccer, scouts, and other activities. He does manage to find a little time for himself for playing on the church softball team, intramural basketball, and the occasional round of golf.
Advice for postdoctoral fellows
1. Sullivan JC, Wang B, Boesen EI, D'Angelo G, Pollock JS, Pollock DM. Novel use of ultrasound to examine regional blood flow in the mouse kidney. Am J Physiol Renal Physiol. 297(1):F228-F235, 2009. 2. Nakano D, Pollock DM. Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats. Hypertension 53(2):324-330, 2009. 3. Schneider MP, Inscho EW, Pollock DM. Attenuated vasoconstrictor responses to endothelin in afferent arterioles during a high-salt diet. Am J Physiol Renal Physiol 292(4):F1208-F1214, 2007. 4. Schneider MP, Boesen EI, Pollock DM. Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol 47:731-759, 2007. 5. Pollock DM, Pollock JS. Evidence for endothelin involvement in the response to high salt. Am. J. Physiol. Renal Physiol. 281: F144-F150, 2001. 6. Treiber FA, Jackson RW, Davis H, Pollock JS, Kapuku G, Mensah GA, Pollock DM. Racial differences in endothelin-1 at rest and in response to acute stress in adolescent males. Hypertension 35(3):722-725, 2000.
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